Results 111 to 120 of about 262,665 (314)
Ultrasensitive Electrochemical Biosensor for Rapid Screening of Chemicals with Estrogenic Effect
BiosensorsEstrogenic chemicals are widely distributed and structurally diverse. They primarily disrupt estrogen-related metabolism in animals or humans by mimicking the agonistic receptor effects of natural estrogens, thereby influencing the transcription of ...
Ruixin Li +4 more
doaj +1 more source
Advanced Science, EarlyView.A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu +8 more
wiley +1 more source
Current status of estrogen and progesterone receptors in breast cancer [PDF]
, 1977 William McGuire +3 more
openalex +1 more source
Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8
Advanced Science, EarlyView.Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong +11 more
wiley +1 more source
The estrogen cytosol receptor of female ovine pituitary [PDF]
, 1975 Phyllis M. Wise, Anita H. Payne
openalex +1 more source
Advanced Science, EarlyView.Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao +16 more
wiley +1 more source
SOLUBLE BIOSPECIFIC MACROMOLECULE FOR PURIFICATION OF ESTROGEN RECEPTOR [PDF]
, 1978 J. Mešter, P. Hubert, E.E. Baulieu
openalex +1 more source
Advanced Science, EarlyView.Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu +14 more
wiley +1 more source
Advanced Science, EarlyView.This study identified that STK33 may serve as a target of Bufalin, which induces the degradation of STK33 and inhibits the growth of TNBC. Furthermore, STK33 is highly expressed in TNBC and enhances TNBC cell proliferation by phosphorylating and stabilizing CCAR1.
Shilong Jiang +11 more
wiley +1 more source