Results 131 to 140 of about 2,614,131 (297)

Screening of BindingDB database ligands against EGFR, HER2, Estrogen, Progesterone and NF-kB receptors based on machine learning and molecular docking [PDF]

open access: yesarXiv
Breast cancer, the second most prevalent cancer among women worldwide, necessitates the exploration of novel therapeutic approaches. To target the four subgroups of breast cancer "hormone receptor-positive and HER2-negative, hormone receptor-positive and HER2-positive, hormone receptor-negative and HER2-positive, and hormone receptor-negative and HER2 ...
arxiv  

New generation estrogen receptor-targeted agents in breast cancer: present situation and future prospectives

open access: yesActa Materia Medica
Endocrine therapy that blocks estrogen receptor signaling has been effective for decades as a primary treatment choice for breast cancer patients expressing the estrogen receptor.
Jian Min   +5 more
doaj   +1 more source

Ultrasensitive Electrochemical Biosensor for Rapid Screening of Chemicals with Estrogenic Effect

open access: yesBiosensors
Estrogenic chemicals are widely distributed and structurally diverse. They primarily disrupt estrogen-related metabolism in animals or humans by mimicking the agonistic receptor effects of natural estrogens, thereby influencing the transcription of ...
Ruixin Li   +4 more
doaj   +1 more source

Estrogen receptor signaling mechanisms.

open access: yesAdvances in Protein Chemistry and Structural Biology, 2019
N. Fuentes, P. Silveyra
semanticscholar   +1 more source

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