Results 191 to 200 of about 276,776 (266)

Rethinking Treatment Priorities in Estrogen Receptor-Low Breast Cancer. [PDF]

J Clin Oncol
Freeman JQ, Nanda R, Howard FM.
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

An estrogen receptor/E2F1/CDKN3 axis protects from UV-induced skin cancers in females. [PDF]

EMBO Rep
Lukowicz C, Winkler C, Roger C, Fowler JC, Tsai YC, Meuli J, Claudinot S, Chang YT, Iselin C, Jones PH, Guenova E, Jafari P, Michalik L.   +12 more
europepmc   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Genetic regulation of the estrogen receptor and inherited predisposition to breast cancer. [PDF]

Proc Natl Acad Sci U S A
Pierce SB, Kortbawi H, Gulsuner S, Mandell JB, Lee MK, Walsh T, King MC.   +6 more
europepmc   +1 more source

A Short Total Synthesis of the Daucane Sesquiterpenoid Ferutinin

European Journal of Organic Chemistry, EarlyView.
Only nine steps were required to access the bioactive daucane sesquiterpene ester ferutinin (1) from 3‐methyl‐2‐cyclopentenone (3) and allyl p‐tolyl sulfoxide. A one‐pot 1,4‐addition/aldol sequence was used to rapidly provide diene 2 (TBS = tert‐butyldimethylsilyl), ring‐closing metathesis of which followed by alkylation and acylation gave rise to the ...
Christiane Osthaar, Yuzhou Wang, Anne Jäger, Peter Metz   +3 more
wiley   +1 more source

Unravelling the effects of selective estrogen receptor modulators on colorectal cancer: a prognostic role for insulin-like growth factor binding protein-5. [PDF]

Clin Sci (Lond)
Su X, Barker RM, McCarthy K, Biernacka K, Mak A, Perks CM.   +5 more
europepmc   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Protocol to Establish Estrogen Receptor-Negative Heterozygous BRCA1 Organoids. [PDF]

Methods Protoc
Deshpande M, Gerhardt J.
europepmc   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source