Results 331 to 340 of about 2,836,003 (403)

Estrogen receptor-α ablation reverses muscle fibrosis and inguinal hernias. [PDF]

J Clin Invest
Potluri T, You T, Yin P, Coon J, Stulberg JJ, Dai Y, Escobar DJ, Lieber RL, Zhao H, Bulun SE.   +9 more
europepmc   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer. [PDF]

Cell Rep Med
Olsen SN, Anderson B, Hatton C, Chu Z, Simpkins C, Wen Y, Bourgeois W, Haarer EL, Brown M, Jeselsohn R, Welm AL, Toska E, Armstrong SA.   +12 more
europepmc   +1 more source

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso, Davide Stolfo, Markus S. Anker, Antoni Bayes‐Genis, Ovidiu Chioncel, Stephane Heymans, Pardeep S. Jhund, Basil S. Lewis, Gary D. Lopaschuk, Lars H. Lund, Arantxa Gonzalez, Matteo Pagnesi, Gabriele Giacomo Schiattarella, Carlo Gabriele Tocchetti, Peter van der Meer, Sophie Van Linthout, Sven Wassmann, B. Daan Westenbrink, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese   +20 more
wiley   +1 more source

Regulatory mechanisms of the Hippo/YAP axis by G-protein coupled estrogen receptor in gastric signet-ring cell carcinoma. [PDF]

Neoplasia
Wang Y, Sun Y, Zhao W, Zhang J, Wang X, Hu F, Han Z, Wang L, Liu L, Liu B, Liu L, Bi B, Sun D, Liu B, Chai J.   +14 more
europepmc   +1 more source

Renal G protein-coupled estrogen receptor 1 regulates the epithelial sodium channel promoting natriuresis to a greater extent in females. [PDF]

Am J Physiol Renal Physiol
Nasci VL, Bopassa JC, Mironova E, Rhoads M, Singh R, Buehler DP, Pollock DM, Pochynyuk OM, Stockand JD, Gohar EY.   +9 more
europepmc   +1 more source

Gelsolin (GSN) as a key regulator in estrogen receptor-positive breast cancer: implications for prognosis, chemotherapy sensitivity, and immune infiltration. [PDF]

Discov Oncol
Lv M, Wang H, Feng G, Nong Q, Tao S, Ma Y, Fang D.   +6 more
europepmc   +1 more source

A Cyclized Helix-Loop-Helix Peptide as a Molecular Scaffold for Cell-Membrane Permeable Inhibitors for the Interaction Between Estrogen Receptor α and Coactivator SRC1. [PDF]

Chembiochem
Fujiwara D, Inaura S, Tanaka Y, Ito-Harashima S, Yamaguchi-Nomoto A, Kawanishi M, Yagi T, Nakase I, Fujii I.   +8 more
europepmc   +1 more source

Current Therapeutic Opportunities for Estrogen Receptor Mutant Breast Cancer. [PDF]

Biomedicines
Palaniappan M.
europepmc   +1 more source