Results 51 to 60 of about 2,614,121 (287)
Journal of Leukocyte Biology, 2016 Estrogens are known modulators of monocyte/macrophage functions; however, the underlying mechanism has not been clearly defined. Recently, a number of estrogen receptor molecules and splice variants were identified that exert different and sometimes ...
V. Pelekanou +9 more
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Archives of Pathology & Laboratory Medicine, 2011 Abstract Context—A new class of estrogen receptors was discovered in 1996 and named estrogen receptor β (ER-B); the traditional estrogen receptor, which until a little more than 10 years ago was thought of as the only estrogen receptor in existence, is now called estrogen receptor α. Estrogen receptor β has at least 5 isoforms, which may
Mamoun Younes, Naoko Honma
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Neuroprotection and Estrogen Receptors [PDF]
Neuroendocrinology, 2012 This review is intended to assess the state of current knowledge on the role of estrogen receptors (ERs) in the neuroprotective effects of estrogens in models for acute neuronal injury and death. We evaluate the overall evidence that estrogens are neuroprotective in acute injury and critically assess the role of ERα, ERβ, GPR 30, and nonreceptor ...
Anne M. Etgen +3 more
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SARS-Cov2 S Protein Features Potential Estrogen Binding Site
Food Technology and Biotechnology, 2021 Research background. During the current SARS-CoV2 pandemic, as well as earlier SARS and MERS epidemics, it has been observed that COVID19-positive women on average tend to have milder symptoms and lower fatality rates than men.
Ante Tomasović +3 more
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FMO Interaction Energy between 17$β$-Estradiol, 17$α$-Estradiol and Human Estrogen Receptor $α$ [PDF]
arXiv, 2020 The estrogen receptor is a nuclear hormone receptor activated by the natural steroid hormone 17$\beta$-estradiol (E2). Fragment molecular orbital (FMO) calculations were performed which allowed us to obtain the interaction energy ($E_{int}$) between E2, 17$\alpha$-estradiol (17$\alpha$-E2) and the human estrogen receptor $\alpha$ ligand-binding domain.
arxiv
Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man.
New England Journal of Medicine, 1994 BACKGROUND AND METHODS Mutations in the estrogen-receptor gene have been thought to be lethal. A 28-year-old man whose estrogen resistance was caused by a disruptive mutation in the estrogen-receptor gene underwent studies of pituitary-gonadal function ...
Eric P. Smith +8 more
semanticscholar +1 more source
Science Translational Medicine, 2015 Inhibition of the PI3K/AKT pathway results in induction of ER-dependent transcriptional activity and susceptibility to anti-estrogen therapy in ER-positive breast cancer.
A. Bosch +27 more
semanticscholar +1 more source
Expression of estrogen and progesterone receptors in astrocytomas: a literature review
ClinicsGliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones.
Cléciton Braga Tavares +11 more
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Pharmacological Reviews, 2015 Estrogens are critical mediators of multiple and diverse physiologic effects throughout the body in both sexes, including the reproductive, cardiovascular, endocrine, nervous, and immune systems.
E. Prossnitz, J. B. Arterburn
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The estrogen receptor and metabolism
Women's HealthAcross the globe, metabolic syndrome, hyperuric acid, and their related diseases, such as cardiovascular disease, diabetes, and insulin resistance, are increasing in incidence due to metabolic imbalances. Due to the pathogenesis, women are more prone to these diseases than men.
Zizi Xiao, Haijun Liu
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