Results 31 to 40 of about 236,396 (261)

Molecular Mechanisms of Endocrine Resistance in Estrogen-Receptor-Positive Breast Cancer

open access: yesFrontiers in Endocrinology, 2021
The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive breast cancer. The main strategy for the treatment of estrogen receptor-positive breast cancers is blocking the estrogen action on estrogen receptors by ...
Esmael Besufikad Belachew   +2 more
doaj   +1 more source

Estrogen Receptor β

open access: yesArchives of Pathology & Laboratory Medicine, 2011
Abstract Context—A new class of estrogen receptors was discovered in 1996 and named estrogen receptor β (ER-B); the traditional estrogen receptor, which until a little more than 10 years ago was thought of as the only estrogen receptor in existence, is now called estrogen receptor α. Estrogen receptor β has at least 5 isoforms, which may
Mamoun, Younes, Naoko, Honma
openaire   +2 more sources

Estrogen and progesterone receptor expression in breast carcinoma

open access: yesJournal of Pathology of Nepal, 2011
Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak   +7 more
doaj   +1 more source

Stratification of Estrogen Receptor-Negative Breast Cancer Patients by Integrating the Somatic Mutations and Transcriptomic Data

open access: yesFrontiers in Genetics, 2021
Patients with estrogen receptor-negative breast cancer generally have a worse prognosis than estrogen receptor-positive patients. Nevertheless, a significant proportion of the estrogen receptor-negative cases have favorable outcomes. Identifying patients
Jie Hou   +3 more
doaj   +1 more source

The Effect of Estrogen Receptor Status on Survival in Breast Cancer Patients in Ethiopia. Retrospective Cohort Study

open access: yesBreast Cancer: Targets and Therapy, 2022
Abebe Muche Belete,1 Yared Asmare Aynalem,2 Belete Negese Gemeda,2 Tefera Mulugeta Demelew,3 Wondimeneh Shibabaw Shiferaw2 1Department of Biomedical Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Nursing, Debre Berhan University,
Belete AM   +4 more
doaj  

The importance of simultaneous determination of breast cancer biomarkers [PDF]

open access: yesArchive of Oncology, 2002
It is shown that steroid hormone receptors by themselves are not sufficiently strong prognostic factors in management of breast cancer. For that reason, simultaneous consideration of different biomarkers seems to be more appropriate for clinical use, i.e.
Markićević Milan   +3 more
doaj   +1 more source

UJI IN SILICO SENYAWA 2,6-DIHIDROKSIANTRAQUINON SEBAGAI LIGAN PADA RESEPTOR ESTROGEN ALFA

open access: yesJurnal Farmasi Sains dan Komunitas, 2015
Previous studies has shown that estrogen receptor alpha that binds to estrogen may increase cancer cell proliferation, thus estrogen receptor alpha can be targeted to cure breast cancer.
Felicia Fraulein Setiawan   +1 more
doaj   +1 more source

Function of G-Protein-Coupled Estrogen Receptor-1 in Reproductive System Tumors

open access: yesJournal of Immunology Research, 2016
The G-protein-coupled estrogen receptor-1 (GPER-1), also known as GPR30, is a novel estrogen receptor mediating estrogen receptor signaling in multiple cell types.
Hongyan Qian   +3 more
doaj   +1 more source

Research progress of estrogen receptor on prostate cancer [PDF]

open access: yesYixue xinzhi zazhi, 2020
Prostate cancer is the most common malignant tumor and the second most common cause of cancer death in men. Estrogen receptors (ERs) are member of steroid hormone receptor superfamily.
Gang-Lin SU   +3 more
doaj   +1 more source

Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function

open access: yesJournal of Diabetes Research, 2015
Clinical trials and animal studies have revealed that loss of circulating estrogen induces rapid changes in whole body metabolism, fat distribution, and insulin action.
Anisha A. Gupte   +2 more
doaj   +1 more source

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