Results 21 to 30 of about 236,396 (261)

Dopaminergic activation of estrogen receptors induces fos expression within restricted regions of the neonatal female rat brain. [PDF]

open access: yesPLoS ONE, 2008
Steroid receptor activation in the developing brain influences a variety of cellular processes that endure into adulthood, altering both behavior and physiology.
Kristin M Olesen, Anthony P Auger
doaj   +1 more source

Estrogen-Independent Activation of Estrogen Receptors [PDF]

open access: yesHypertension, 2011
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias, Barton   +2 more
openaire   +2 more sources

Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer

open access: yesNeoplasia: An International Journal for Oncology Research, 2010
Targeting the estrogen receptor is an important strategy in breast cancer therapy. However, although inhibiting estrogen receptor function with specific estrogen receptor modulators can achieve a primary response in cancer patients, intrinsic or ...
Huajun Zhao   +11 more
doaj   +1 more source

Molecular mechanism of estrogen–estrogen receptor signaling [PDF]

open access: yesReproductive Medicine and Biology, 2016
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin   +4 more
openaire   +3 more sources

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

open access: yesGenome Biology, 2019
Background VirtUaL ChIP-seq Analysis through Networks (VULCAN) infers regulatory interactions of transcription factors by overlaying networks generated from publicly available tumor expression data onto ChIP-seq data.
Andrew N. Holding   +6 more
doaj   +1 more source

Efficacy of Fractional Laser on Steroid Receptors in GSM Patients

open access: yesBioengineering, 2023
Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy.
Stella Catunda Pinho   +9 more
doaj   +1 more source

Immunoekspresi Reseptor α pada Poket Periodontal Lebih Banyak daripada Reseptor Estrogen β

open access: yesJournal of Dentistry Indonesia, 2013
Studies have been reported on the association between menopause and periodontal disease related to estrogen deficiency. Although the estrogen receptor has been demonstrated on some oral tissues, the presence of estrogen receptors on periodontal pockets ...
Yuliana Mahdiyah Da’at Arina
doaj   +1 more source

An emerging generation of endocrine therapies in breast cancer: a clinical perspective

open access: yesnpj Breast Cancer, 2023
Anti-estrogen therapy is a key component of the treatment of both early and advanced-stage hormone receptor (HR)-positive breast cancer. This review discusses the recent emergence of several anti-estrogen therapies, some of which were designed to ...
Rima Patel   +3 more
doaj   +1 more source

Expression and function of estrogen receptors and estrogen-related receptors in the brain and their association with Alzheimer’s disease

open access: yesFrontiers in Endocrinology, 2023
While estrogens are well known for their pivotal role in the female reproductive system, they also play a crucial function in regulating physiological processes associated with learning and memory in the brain. Moreover, they have neuroprotective effects
Kaoru Sato   +3 more
doaj   +1 more source

Genistein modulates the estrogen receptor and suppresses angiogenesis and inflammation in the murine model of peritoneal endometriosis

open access: yesJournal of Traditional and Complementary Medicine, 2018
The purpose of this study was to investigate the effect of genistein administration on the modulation of the estrogen receptor, inhibition of inflammation and angiogenesis in the murine model of peritoneal endometriosis.
Sutrisno Sutrisno   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy