Results 21 to 30 of about 1,539,304 (263)

Molecular Mechanisms of Endocrine Resistance in Estrogen-Receptor-Positive Breast Cancer

Frontiers in Endocrinology, 2021
The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive breast cancer. The main strategy for the treatment of estrogen receptor-positive breast cancers is blocking the estrogen action on estrogen receptors by ...
Esmael Besufikad Belachew, Esmael Besufikad Belachew, Dareskedar Tsehay Sewasew   +2 more
doaj   +1 more source

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers [PDF]

, 2013
Introduction: We examined if a combination of proliferation markers and estrogen receptor (ER) activity could predict early versus late relapses in ER-positive breast cancer and inform the choice and length of adjuvant endocrine therapy.
Luca Gianni, Del Conte, Gianluca, Sotiriou, Christos, Pusztai, Lajos, Lajos Pusztai, Karn, Thomas, Symmans, W. Fraser, Libero Santarpia, Volkmar Müller, Santarpia, Libero, Sven Becker, Milvia Zambetti, Müller, Volkmar, Symmans, W Fraser, Benjamin Haibe-Kains, Kelly, Catherine M, Rody, Achim, Catherine M Kelly, Giampaolo Bianchini, Marcus Schmidt, Gianluca Del Conte, Gianni, Luca, Bianchini, Giampaolo, W Fraser Symmans, Haibe-Kains, Benjamin, Thomas Karn, Achim Rody, Schmidt, Marcus, Fasolo, Angelica, Takayuki Iwamoto, Angelica Fasolo, Holtrich, Uwe, Kelly, Catherine M., Yuan Qi, Christos Sotiriou, Uwe Holtrich, Iwamoto, Takayuki, Qi, Yuan, Becker, Sven, Zambetti, Milvia   +39 more
core   +2 more sources

Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]

, 2013
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo, Claudia Colussi (377816), Luis Jaime Castro-Vega (409816), Londono-Vallejo Arturo, Londono-Vallejo, Arturo, Simona Nanni, Colussi Claudia, Nanni, Simona, Pontecorvi, Alfredo, Castro-Vega, Luis Jaime, Carlo Gaetano (110837), Capogrossi, Maurizio C., Re, Agnese, Silvia Bacchetti (409817), Aiello Aurora, Valentina Benvenuti (409815), Guffanti Alessandro, Felsani, Armando, Claudia Colussi, Simona Nanni (110816), Maurizio C Capogrossi, Felsani Armando, Bacchetti, Silvia, Luis Jaime Castro-Vega, Benvenuti, Valentina, Armando Felsani (132772), Re Agnese, Pontecorvi Alfredo, Antonella Farsetti, Alessandro Guffanti, Gaetano, Carlo, Armando Felsani, Agnese Re, Castro-Vega Luis Jaime, Arturo Londono-Vallejo (5654743), Aurora Aiello, Nanni Simona, Alessandro Guffanti (5573), Maurizio C. Capogrossi (103525), Gaetano Carlo, Carlo Gaetano, Agnese Re (409814), Aurora Aiello (358824), Guffanti, Alessandro, Farsetti Antonella, Farsetti, Antonella, Capogrossi Maurizio C., Alfredo Pontecorvi, Alfredo Pontecorvi (409818), Antonella Farsetti (110827), Silvia Bacchetti, Aiello, Aurora, Benvenuti Valentina, Bacchetti Silvia, Colussi, Claudia, Valentina Benvenuti   +55 more
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The Effect of Estrogen Receptor Status on Survival in Breast Cancer Patients in Ethiopia. Retrospective Cohort Study

Breast Cancer: Targets and Therapy, 2022
Abebe Muche Belete,1 Yared Asmare Aynalem,2 Belete Negese Gemeda,2 Tefera Mulugeta Demelew,3 Wondimeneh Shibabaw Shiferaw2 1Department of Biomedical Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Nursing, Debre Berhan University,
Belete AM, Aynalem YA, Gemeda BN, Demelew TM, Shiferaw WS   +4 more
doaj  

Estrogen and progesterone receptor expression in breast carcinoma

Journal of Pathology of Nepal, 2011
Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak, R Bashyal, CB Pun, S Shrestha, S Bastola, S Neupane, BR Poudel, MC Lee   +7 more
doaj   +1 more source

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen [PDF]

, 2012
SynthSys is a Centre for Integrative Systems Biology (CISB) funded by BBSRC and EPSRC, reference BB/D019621/1.Background: Estrogen receptors alpha (ER) are implicated in many types of female cancers, and are the common target for anti-cancer therapy ...
Harrison, David J, Kenneth Macleod, Yamaguchi, Azusa, Macleod, Kenneth, Galina Lebedeva, David J Harrison, Lebedeva, Galina, Langdon, Simon P., Langdon, Simon P, Azusa Yamaguchi, Harrison, David J., Simon P Langdon   +11 more
core   +1 more source

Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Beatrice E. Bachmeier, Ulrich Pfeffer, Killian, Peter H., Blengio, Fabiola, Valentina Mirisola, Romeo, Francesco, Dell'Eva, Raffaella, Pfeffer, Ulrich, Luca Generoso, Fabiola Blengio, Alessia Esposito, Raffaella Dell’Eva, Mirisola, Valentina, Generoso, Luca, Albini, Adriana, Adriana Albini, Peter H. Killian, Bachmeier, Beatrice E., Esposito, Alessia, Francesco Romeo   +19 more
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The importance of simultaneous determination of breast cancer biomarkers [PDF]

Archive of Oncology, 2002
It is shown that steroid hormone receptors by themselves are not sufficiently strong prognostic factors in management of breast cancer. For that reason, simultaneous consideration of different biomarkers seems to be more appropriate for clinical use, i.e.
Markićević Milan, Todorović-Raković Nataša, Kanjer Ksenija, Nikolić-Vukosavljević Dragica   +3 more
doaj   +1 more source

Stratification of Estrogen Receptor-Negative Breast Cancer Patients by Integrating the Somatic Mutations and Transcriptomic Data

Frontiers in Genetics, 2021
Patients with estrogen receptor-negative breast cancer generally have a worse prognosis than estrogen receptor-positive patients. Nevertheless, a significant proportion of the estrogen receptor-negative cases have favorable outcomes. Identifying patients
Jie Hou, Xiufen Ye, Yixing Wang, Chuanlong Li   +3 more
doaj   +1 more source

UJI IN SILICO SENYAWA 2,6-DIHIDROKSIANTRAQUINON SEBAGAI LIGAN PADA RESEPTOR ESTROGEN ALFA

Jurnal Farmasi Sains dan Komunitas, 2015
Previous studies has shown that estrogen receptor alpha that binds to estrogen may increase cancer cell proliferation, thus estrogen receptor alpha can be targeted to cure breast cancer.
Felicia Fraulein Setiawan, Enade Perdana Istyastono   +1 more
doaj   +1 more source