Results 81 to 90 of about 446,168 (357)

Estrogen receptor cytochemistry by fluorescent estrogen. [PDF]

Journal of Histochemistry & Cytochemistry, 1980
A recently synthesized fluorescein-labeled estrogen (17FE, 1-(N)-fluoresceinyl-estrone-thiosemicarbazone) interacts with estrogen-target cells like the native hormone and visualizes the uptake, transport, and distribution of estrogen in intact target cells.
G. Fabris, C Y Meyers, E. Marchetti, Italo Nenci, W B Dandliker, Andrea Marzola   +5 more
openaire   +3 more sources

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Estrogen alpha receptor antagonists for the treatment of breast cancer: a review

Chemistry Central Journal, 2018
Background Cancer is at present one of the leading causes of death in the world. It accounts for 13% of deaths occurred worldwide and is continuously rising, with an estimated million of deaths up to 2030.
Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan   +2 more
doaj   +1 more source

Distinct Effects of Estrogen on Mouse Maternal Behavior: The Contribution of Estrogen Synthesis in the Brain. [PDF]

PLoS ONE, 2016
Estrogen surge following progesterone withdrawal at parturition plays an important role in initiating maternal behavior in various rodent species. Systemic estrogen treatment shortens the latency to onset of maternal behavior in nulliparous female rats ...
Gen Murakami
doaj   +1 more source

Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana, Bachmeier, Beatrice E., Blengio, Fabiola, Dell'Eva, Raffaella, Esposito, Alessia, Generoso, Luca, Killian, Peter H., Mirisola, Valentina, Pfeffer, Ulrich, Romeo, Francesco   +9 more
core   +1 more source

Molecular mechanism of estrogen–estrogen receptor signaling [PDF]

Reproductive Medicine and Biology, 2016
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin, Ayaz, Gamze, User, Sirma Damla, Gupur, Gizem, Muyan, Mesut   +4 more
openaire   +4 more sources

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]

, 2017
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core   +1 more source

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers [PDF]

, 2013
Introduction: We examined if a combination of proliferation markers and estrogen receptor (ER) activity could predict early versus late relapses in ER-positive breast cancer and inform the choice and length of adjuvant endocrine therapy.
Achim Rody, AJ Minn, Angelica Fasolo, B Haibe-Kains, B Thurlimann, Benjamin Haibe-Kains, C Bellera, C Davies, C Desmedt, C Kim, C Sotiriou, Catherine M Kelly, Christos Sotiriou, CJ van de Velde, D Sgroi, E Amir, G Bianchini, G Bianchini, G Tang, Giampaolo Bianchini, Gianluca Del Conte, H Jin, I Jatoi, JS Parker, KR Hess, KS Albain, Lajos Pusztai, Libero Santarpia, Luca Gianni, M Dowsett, M Filipits, M Schmidt, Marcus Schmidt, Milvia Zambetti, MJ Ellis, MJ van de Vijver, MM Regan, P Dubsky, R Simon, S Loi, S Loi, S Paik, Sven Becker, Takayuki Iwamoto, Thomas Karn, TO Nielsen, Uwe Holtrich, Volkmar Müller, W Fraser Symmans, WF Symmans, WR Miller, Y Wang, Y Zhang, Yuan Qi   +53 more
core   +1 more source