Results 41 to 50 of about 149,401 (350)
Estrogen receptor ß is involved in the anorectic action of estrogen [PDF]
International Journal of Obesity, 2002 Estrogen has been implicated in feeding behavior and adiposity. This study was undertaken to elucidate the mechanism underlying the anti-obesity and anorectic action of estrogen and the role of estrogen receptor (ER) in the central nervous system.Ovariectomy in 8-week-old female Wistar rats induced hyperphagia along with an increase in body weight and ...
Yasuyoshi Ouchi +11 more
openaire +2 more sources
Role of estrogen receptors in health and disease
Frontiers in Endocrinology, 2022 Estrogen receptors (ERs) regulate multiple complex physiological processes in humans. Abnormal ER signaling may result in various disorders, including reproductive system-related disorders (endometriosis, and breast, ovarian, and prostate cancer), bone ...
Peng Chen, Bo Li, Ling Ou-Yang
doaj +1 more source
The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells [PDF]
, 2017 open12noBreast cancer (BC) is one of the major causes of cancer death in women and is closely related to hormonal dysregulation. Estrogen receptor (ER)-positive BCs are generally treated with anti hormone therapy using antiestrogens or aromatase ...
CARRA, Serena +11 more
core +3 more sources
Estrogen Receptors Alpha and Beta in Acute Myeloid Leukemia [PDF]
Cancers, 2020 Estrogen receptor (ER) signaling has been widely studied in a variety of solid tumors, where the differential expression of ERα and ERβ subtypes can impact prognosis. ER signaling has only recently emerged as a target of interest in acute myeloid leukemia (AML), an aggressive hematological malignancy with sub-optimal therapeutic options and poor ...
Alessia Roma, Paul A. Spagnuolo
openaire +2 more sources
Ecdysteroids: A novel class of anabolic agents? [PDF]
, 2015 Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
BOTRE', Francesco +5 more
core +2 more sources
Reproductive Biology and Endocrinology, 2009 Background Estrogen is known to play role in temporomandibular joint (TMJ) disorders and estrogen effects can be mediated by estrogen receptor (ER) alpha present in the TMJ.
Bellinger Larry L +3 more
doaj +1 more source
Interdisciplinary Neurosurgery, 2020 Background: The majority of prolactin-secreting pituitary macroadenomas are effectively managed with dopamine-agonist therapy alone. Although surgical resection and radiotherapy are second- and third-line treatment options, there remains a paucity of ...
Zachary K. Christian +5 more
doaj +1 more source
Pancreatic insulin content regulation by the estrogen receptor ER alpha. [PDF]
PLoS ONE, 2008 The function of pancreatic beta-cells is the synthesis and release of insulin, the main hormone involved in blood glucose homeostasis. Estrogen receptors, ER alpha and ER beta, are important molecules involved in glucose metabolism, yet their role in ...
Paloma Alonso-Magdalena +8 more
doaj +1 more source
The Isoforms of Estrogen Receptor Alpha and Beta in Thyroid Cancer
Frontiers in Oncology, 2022 The incidence of thyroid cancer was predominant in women, indicating that the sex hormone may have a role in thyroid cancer development. Generally, the sex hormone exerts its function by binding to the correspondent nuclear receptors. Therefore, aberrant of these receptors may be involved in the development of thyroid cancer.
Zhongqin Gong +10 more
openaire +3 more sources
Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
, 2016 Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source