Results 21 to 30 of about 73,581 (158)
BMC Cancer, 2018 Background The relevance of estrogen receptor (ER) expression in pancreatic ductal adenocarcinoma (PDAC) is largely unknown. Clinical trials targeting ER with selective estrogen receptor modulators in pancreatic cancer did not show any benefit.
Hendrik Seeliger +7 more
doaj +1 more source
Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. [PDF]
PLoS ONE, 2009 While premature suture fusion, or craniosynostosis, is a relatively common condition, the cause is often unknown. Estrogens are associated with growth plate fusion of endochondral bones.
Aaron W James +8 more
doaj +1 more source
Estrogen receptor beta in breast cancer
Molecular and Cellular Endocrinology, 2014 Estrogen is essential for growth and development of the mammary glands and has been associated with the promotion and growth of breast cancer and in line with this, most human breast cancers are initially estrogen-dependent and undergo regression when deprived of their supporting hormone.
Haldosén, Lars-Arne +2 more
openaire +2 more sources
Proceedings, 2019 Estrogen receptor-beta (ER-beta) is a drug target for memory consolidation in postmenopausal [...]
Alicia M. Hanson +10 more
doaj +1 more source
Genistein as an Estrogen Receptor-Beta Selective Phytoestrogen: Molecular Docking Insights for Advanced Wound Healing Therapies [PDF]
BIO Web of ConferencesWound healing is highly hormonal based and is stepwise process involving inflammation, proliferation, and remodeling .Estrogen is a key regulator having two receptor subtypes having various functions.
Varma Greeshma +2 more
doaj +1 more source
Expression levels of sex hormone receptors in brains ofJapanese medaka, Oryzias latipes (Actinopterygii: Beloniformes: Adrianichthyidae) [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. In teleost fishes, the brain is the target organ for sex steroid hormones. The actions of sex steroid hormones are mediated by their receptors and play an important role in the regulation of endocrine function in the brain.
A. Ngamniyom, Y. Sasayama
doaj +3 more sources
Synthesis and Evaluation of (1,4-Disubstituted)-1,2,3-triazoles as Estrogen Receptor Beta Agonists
Scientia Pharmaceutica, 2022 Estrogen receptors (ER) are nuclear hormone receptors which are responsible for sex hormone signaling in women. A series of (1,4-disubstituted)-1,2,3-triazoles 5–21 were prepared by reaction of azidophenols with terminal alkynes under Fokin reaction ...
Edward A. Wetzel +4 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2010 The biology of breast cancer is closely releted to sex steroid hormones. Estrogen receptor beta is overexpressed in around 70% breast cancer cases, referrd to as "ER positive".
Mariusz Kuźmicki +6 more
doaj +1 more source
Role of estrogen receptors in health and disease
Frontiers in Endocrinology, 2022 Estrogen receptors (ERs) regulate multiple complex physiological processes in humans. Abnormal ER signaling may result in various disorders, including reproductive system-related disorders (endometriosis, and breast, ovarian, and prostate cancer), bone ...
Peng Chen, Bo Li, Ling Ou-Yang
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Estrogens and estrogen-like molecules can modify the biology of several cell types. Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of estrogen receptors, while the G protein-coupled estrogen receptor 1 (GPER-1 ...
Felipe A. Bustamante-Barrientos +14 more
doaj +1 more source