Do Estrogens improve bone mass in osteoporotic women over ten years of menopause
A retrospective analysis of 24 patients with established osteoporosis and with ten or more years of menopause treated with conjugated estrogen, progesterone and calcium followed for one year has been performed.
Vera Lucia Szejnfeld +4 more
doaj +1 more source
ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju +11 more
wiley +1 more source
Successful Pregnancies Following Hormone Replacement Therapy in a Patient with Premature Ovarian Failure: A Case Report [PDF]
Premature ovarian failure is a serious life-changing condition that affects young women, remains an enigma and the researcher’s challenge. Spontaneous pregnancy in a patient with POF is uncommon.
SUNIL KUMAR K.S. +2 more
doaj
Hormone replacement therapy and prevention of vertebral fractures: a meta-analysis of randomised trials [PDF]
BACKGROUND: Hormone replacement therapy (HRT) is often seen as the treatment of choice for preventing fractures in women. We undertook a recent meta-analysis of randomised trials which suggested that HRT reduced non-vertebral fractures by 30%.
Bell-Syer, Sally E.M. +1 more
core +3 more sources
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji +8 more
wiley +1 more source
Ryzyko choroby zatorowo-zakrzepowej związane z terapią hormonalną okresu okołomenopauzalnego
Decision on implementing hormone therapy in perimenopausal woman has to be based on analysis of potentialrisks and benefits of such treatment. Although rarely observed, one of the most serious complication ofhormonal therapy is thromboembolic disease ...
Wojciech Kwaśniewski +2 more
doaj
Treatment of symptoms of the menopause: an endocrine society clinical practice guideline [PDF]
Objective: The objective of this document is to generate a practice guideline for the management and treatment of symptoms of the menopause. Participants: The Treatment of Symptoms of the Menopause Task Force included six experts, a methodologist, and
Davis, Susan R. +6 more
core +1 more source
Chronic intermittent hypoxia induces premature senescence of osteoprogenitor cells in long bone metaphysis via HIF1α‐mediated EZH2‐H3k27me3 downregulation, leading to impaired bone growth. Restoration of H3K27me3 level via UTX inhibition rescues osteogenesis and growth impairment in young mice.
Xiaonan Liu +7 more
wiley +1 more source
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes [PDF]
Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen)
Barnett, A. H. +5 more
core +1 more source

