Results 101 to 110 of about 50,421 (294)

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial [PDF]

, 2002
Background: Throughout the usual LDL cholesterol range in Western populations, lower blood concentrations are associated with lower cardiovascular disease risk.
Heart Protection Study Collaborative Group
core   +1 more source

Advances in the relationship between female intracranial aneurysmal subarachnoid hemorrhage and estrogen deficiency

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
The mortality and morbidity rate of subarachnoid hemorrhage is quite high. The incidence of intracranial aneurysmal subarachnoid hemorrhage in women, especially in postmenopausal women, is significantly higher than that in men, which is related to ...
Feng-xuan TIAN
doaj  

Machine Learning‐Enabled Prediction of pH‐Responsive Curcumin Release From Self‐Assembled Nanomicelles

Journal of Applied Polymer Science, EarlyView.
Curcumin encapsulation in nanomicelles coupled with a machine learning–guided model for predicting its release profile. ABSTRACT This work, leveraging machine‐learning algorithms, focuses on the design and in vitro evaluation of oil‐in‐water surfactant‐based nanomicelles as a novel curcumin formulation with comparable cytotoxic effects against MCF‐7 ...
Abbas Rahdar, Sonia Fathi‐karkan, Maryam Shirzad, M. Ali Aboudzadeh   +3 more
wiley   +1 more source

Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]

, 2009
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Ochsenkühn, Robert, Toth, Bettina, Scholz, Christoph, Jeschke, Udo, Schulze, Sandra, Kuhn, Christina, Friese, Klaus   +6 more
core   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Local variation in age‐related cortical expansion within and between cross‐sections of distal human long bones

The Anatomical Record, EarlyView.
Abstract Cortical bone expansion is an age‐related process where, through endosteal resorption and periosteal apposition, cross‐sectional diameter increases while cortical thickness decreases in long bone diaphyses. Local variation has been observed in this process between cross‐sectional locations, but few studies have examined directional variation ...
Gregory J. Wehrman, Alice F. Gooding, Adam D. Sylvester, Dawnie W. Steadman, Benjamin M. Auerbach   +4 more
wiley   +1 more source

Bezafibrate in men with lower extremity arterial disease: randomised controlled trial. [PDF]

, 2002
OBJECTIVE: To assess the effect of bezafibrate on the risk of coronary heart disease and stroke in men with lower extremity arterial disease. DESIGN: Double blind placebo controlled randomised trial.
Cooper, Jackie, Meade, Tom, Cook, Claire, Zuhrie, Riaz   +3 more
core   +1 more source

ENDOMETRIUM AND HORMONAL REPLACEMENT THERAPY

Zdravniški Vestnik, 2008
BACKGROUND Estrogen induces endometrial stimulation and increases the risk for endometrial hyperplasia and endometrial cancer. Added progestin diminishes endometrial stimulation.The risk for endometrial hyperplasia with hormonal replacement therapy (HRT)
Branka Žegura
doaj  

Timing Matters: Effects of Early and Late Estrogen Replacement Therapy on Glucose Metabolism and Vascular Reactivity in Ovariectomized Aged Wistar Rats. [PDF]

J Renin Angiotensin Aldosterone Syst, 2023
Ramírez-Hernández D, López-Sánchez P, Lezama-Martínez D, Kuyoc-Arroyo NM, Rodríguez-Rodríguez JE, Fonseca-Coronado S, Valencia-Hernández I, Flores-Monroy J.   +7 more
europepmc   +1 more source

Editorial Commentary: Estrogen Influences Shoulder Health

Arthroscopy, EarlyView.
Abstract Estrogen influences bone mineral density, muscle quality and quantity, and collagen synthesis, rotator cuff tearing, worse outcomes after rotator cuff repair, hyperlaxity, and adhesive capsulitis. In this commentary, we discuss the potential explanations for the highly significant associations between hormonal systemic birth control and a ...
Peter Chalmers, Robert Tashjian
wiley   +1 more source