Results 121 to 130 of about 95,231 (351)

ENDOMETRIUM AND HORMONAL REPLACEMENT THERAPY

open access: yesZdravniški Vestnik, 2008
BACKGROUND Estrogen induces endometrial stimulation and increases the risk for endometrial hyperplasia and endometrial cancer. Added progestin diminishes endometrial stimulation.The risk for endometrial hyperplasia with hormonal replacement therapy (HRT)
Branka Žegura
doaj  

Timing Matters: Effects of Early and Late Estrogen Replacement Therapy on Glucose Metabolism and Vascular Reactivity in Ovariectomized Aged Wistar Rats. [PDF]

open access: yesJ Renin Angiotensin Aldosterone Syst, 2023
Ramírez-Hernández D   +7 more
europepmc   +1 more source

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

open access: yes, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien   +3 more
core  

A principal stratification approach to assess the differences in prognosis between cancers caused by hormone replacement therapy and by other factors [PDF]

open access: yes, 2010
Several recent studies have reported that women who have used hormone replacement therapy (HRT), and developed breast cancer, tend to have a better prognosis than women with breast cancer who have not used HRT.
Humphreys, Keith   +2 more
core   +1 more source

Genetically Engineered Light‐Responsive In Situ Hydrogels for Immunomodulation and Multimodal Therapy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Cysteine‐tagged silk‐elastin‐like proteins, a family of tri‐block chimeric proteins that consist of a photothermal agent binding motif, silk motif, and elastin motif is developed to form a responsive in situ hydrogel for late‐stage and metastatic triple‐negative breast cancer.
Xinchen Shen   +11 more
wiley   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

The risk of ovarian cancer in hormone replacement therapy users: a systematic review and meta-analysis

open access: yesFrontiers in Endocrinology
BackgroundWith the increasing use of hormone replacement therapy (HRT), there is a need to understand its impact on the occurrence of female malignant tumors.
Hongqin Xiang   +3 more
doaj   +1 more source

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