Results 51 to 60 of about 2,936,436 (245)

Changes of condyle cartilage in orchidectomized rats fed with young coconut juice: Novel preliminary findings [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2010
Androgens play a very important role in building the skeleton in young adults and help to prevent bone loss and osteoporosis in aging men. In addition, in elderly men, bone mass has been related to estrogen levels rather than to testosterone.
Muhammadbakhoree Yusuh, Nattika Phochanukoon, Nisaudah Radenahmad, Mutita Eksomtramate, Praphansri Ruangsri, Anachak Chantanasuksilpa, Anupong Nitiruangjaras   +6 more
doaj  

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Histological Changes in the Fracture Callus Following the Administration of Water Extract of Piper Sarmentosum (Daun Kadok) in Estrogen-Deficient Rats [PDF]

Iranian Journal of Medical Sciences, 2011
Background: The fracture healing is impaired in osteoporosis. Piper sarmentosum is a plant, which contains potent antioxidant, naringenin that may enhance fracture healing. The present histological study aimed to determine the effects of water extract of
Mohamed Abdalla Estai, Ima Nirwana Soelaiman, Ahmad Nazrun Shuid, Srijit Das, Aishah Mohd Ali, Farihah Hj Suhaimi   +5 more
doaj  

Functional and molecular neuroimaging of menopause and hormone replacement therapy

Frontiers in Neuroscience, 2014
The level of gonadal hormones to which the female brain is exposed considerably changes across the menopausal transition, which in turn, is likely to be of great relevance for neurodegenerative diseases and psychiatric disorders.
Erika eComasco, Erika eComasco, Vibe Gedsoe Frøkjær, Inger eSundström Poromaa   +3 more
doaj   +1 more source

A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9. [PDF]

PLoS ONE, 2016
Poor outcome in response to hepatitis C virus, including higher viral load, hepatocellular carcinoma and cirrhosis, is more associated with men and postmenopausal women than with premenopausal women and women receiving hormone replacement therapy ...
Laura Ulitzky, Manuel M Lafer, Mark A KuKuruga, Erica Silberstein, Nicoleta Cehan, Deborah R Taylor   +5 more
doaj   +1 more source

The Current Strategy in Hormonal and Non-Hormonal Therapies in Menopause—A Comprehensive Review

Life, 2023
Menopause is a natural stage of hormonal aging in women, accompanied by a series of symptoms that reduce the quality of life of a fully active person. As no therapy is entirely satisfactory, the race for a better option is in full swing.
Anca Lucia Pop, Bogdana Adriana Nasui, Roxana Georgiana Bors, Ovidiu Nicolae Penes, Ana Gabriela Prada, Eliza Clotea, Simona Crisan, Calin Cobelschi, Claudia Mehedintu, Monica Mihaela Carstoiu, Valentin Nicolae Varlas   +10 more
doaj   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Hormone replacement therapy: perspectives from women, medicine and sociology [PDF]

, 1997
Developed on the boundary between medicine and sociology, this thesis develops a critique of the perspectives of these disciplines through analysis of a study of women's perspectives on hormone replacement therapy.
Griffiths, Frances Ellen, Griffiths, F.E.   +1 more
core  

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Poor Compliance to Hormone Therapy and Decreased Bone Mineral Density in Women with Premature Ovarian Insufficiency. [PDF]

PLoS ONE, 2016
Premature ovarian insufficiency leads to through infertility and estrogen deficiency. Optimal management encompasses estrogen replacement therapy. Long-term outcome of women with POI is not known.
Anne Bachelot, Carole Nicolas, Solenne Gricourt, Jérôme Dulon, Monique Leban, Jean Louis Golmard, Philippe Touraine   +6 more
doaj   +1 more source