Results 41 to 50 of about 50,235 (294)

Distinct roles of estrone and estradiol in endothelial colony‐forming cells

open access: yesPhysiological Reports, 2023
Our current understanding of the relationship between estrogen and human endothelial colony‐forming cell (hECFC) function is based almost exclusively on studies investigating estradiol action at nuclear estrogen receptors.
Alicia Ivory, Andrew S. Greene
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Effects of hormone replacement therapy on depressive and anxiety symptoms after oophorectomy [PDF]

open access: yesMedicinski Glasnik, 2015
Aim To assess the effect of hormone replacement therapy on postoperative depression and anxiety symptoms. Methods In observational prospective study 80 women divided into two groups were evaluated: women who received estrogen and androgen replacement ...
Danijela D. Ðoković   +5 more
doaj  

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

open access: yesAdvanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima   +15 more
wiley   +1 more source

Three‐year follow‐up of the use of a levonorgestrel‐releasing intrauterine system in hormone replacement therapy

open access: yesActa Obstetricia et Gynecologica Scandinavica, 1997
Background. The efficacy of a levonorgestrel‐releasing intrauterine system in opposing endometrial proliferation and in preventing bleeding was studied in peri‐ and postmenopausal women receiving estrogen replacement therapy. Methods.
Satu Suhonen   +2 more
doaj   +1 more source

The History of Estrogen Therapy

open access: yes, 2019
Research on hormone therapies has been evolving rapidly with controversy close behind. The first goal of this project was to investigate a controversy regarding testosterone replacement therapy treatment when associated with lower urinary tract symptoms.
Kohn, Grace, Kohn, Grace.
core   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane   +4 more
wiley   +1 more source

Changes in Hemostasis and Lipid Metabolism in Postmenopausal Women Receiving Hormone Replacement Therapy: Effects of Natural and Synthetic Progestogens

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2004
Objective: In this study, we evaluated hemostatic factors related to cardiovascular disease in postmenopausal women receiving estrogen or combined progestogen replacement therapy.
Li-Fen Teng, Fang-Ping Chen
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Hormone Replacement Therapy Does Not Eliminate Risk Factors for Joint Complications following Total Joint Arthroplasty: A Matched Cohort Study

open access: yesPathophysiology, 2023
Aging causes a reduction in testosterone and estrogen, which is linked to diminished bone mineral density. Hormone replacement therapy and its effect on the outcome of joint arthroplasties is unclear.
Lacee K. Collins   +5 more
doaj   +1 more source

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