Results 21 to 30 of about 2,936,436 (245)

Shereshevsky-Turner syndrome: Estrogen replacement therapy and cardiovascular risk factors [PDF]

open access: yesТерапевтический архив, 2017
Aim. To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT ...
O A Yevstigneeva   +5 more
doaj   +1 more source

Malignancies Associated with Extraovarian Endometriosis: A Literature Review

open access: yesEndocrines, 2021
Endometriosis-associated ovarian malignancies have been well documented. Although these malignancies also occur as extraovarian lesions, little is known about them. Thus, this literature review aimed to further explore these rarely experienced tumors.
Naoki Inoue   +4 more
doaj   +1 more source

Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey

open access: yesGynecology Obstetrics & Reproductive Medicine, 2021
OBJECTIVE: In this study, we aimed to determine the frequency of etiologic factors that causes postmenopausal bleeding. STUDY DESIGN: For the purpose, a total number of 200 women with postmenopausal bleeding were included in the study.
Umit Yasemin Sert   +2 more
doaj   +1 more source

Influence of sexual dimorphism on satellite cell regulation and inflammatory response during skeletal muscle regeneration

open access: yesPhysiological Reports, 2023
After injury, skeletal muscle regenerates thanks to the key role of satellite cells (SC). The regeneration process is supported and coordinated by other cell types among which immune cells. Among the mechanisms involved in skeletal muscle regeneration, a
Charline Jomard, Julien Gondin
doaj   +1 more source

Estradiol and Estrogen-like Alternative Therapies in Use: The Importance of the Selective and Non-Classical Actions

open access: yesBiomedicines, 2022
Estrogen is one of the most important female sex hormones, and is indispensable for reproduction. However, its role is much wider. Among others, due to its neuroprotective effects, estrogen protects the brain against dementia and complications of ...
Szidónia Farkas   +7 more
doaj   +1 more source

Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]

open access: yes, 2010
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Beatrice E. Bachmeier   +19 more
core   +1 more source

Distinct roles of estrone and estradiol in endothelial colony‐forming cells

open access: yesPhysiological Reports, 2023
Our current understanding of the relationship between estrogen and human endothelial colony‐forming cell (hECFC) function is based almost exclusively on studies investigating estradiol action at nuclear estrogen receptors.
Alicia Ivory, Andrew S. Greene
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

High-Dose Estradiol-Replacement Therapy Enhances the Renal Vascular Response to Angiotensin II via an AT2-Receptor Dependent Mechanism

open access: yesAdvances in Pharmacological Sciences, 2015
Physiological levels of estrogen appear to enhance angiotensin type 2 receptor- (AT2R-) mediated vasodilatation. However, the effects of supraphysiological levels of estrogen, analogous to those achieved with high-dose estrogen replacement therapy in ...
Tahereh Safari   +3 more
doaj   +1 more source

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