Estrogen replacement therapy and cardioprotection: mechanisms and controversies
Epidemiological and case-controlled studies suggest that estrogen replacement therapy might be beneficial in terms of primary prevention of coronary heart disease (CHD).
M.T.R. Subbiah
doaj +1 more source
Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Beatrice E. Bachmeier +19 more
core +1 more source
The Combinatory Effects of Glabridin and Tamoxifen on Ishikawa and MCF-7 Cell Lines
Estrogen replacement therapy is commonly used to replace the loss of estrogen in post-menopausal women. However, it is not suitable to be used in women taking tamoxifen as both of the drugs increase the risk of endometrial cancer.
Soe Hui Jen +2 more
doaj +1 more source
The History of Estrogen Therapy [PDF]
Research on hormone therapies has been evolving rapidly with controversy close behind. The first goal of this project was to investigate a controversy regarding testosterone replacement therapy treatment when associated with lower urinary tract symptoms.
Kohn, Grace, Kohn, Grace.
core +2 more sources
Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. [PDF]
OBJECTIVE: To determine the effects of antiplatelet therapy among patients at high risk of occlusive vascular events. DESIGN: Collaborative meta-analyses (systematic overviews).
M. Catalano +9 more
core +1 more source
Targeting mutant estrogen receptors
A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
Suzanne E Wardell +2 more
doaj +1 more source
Estrogen stimulates dimethylarginine dimethylaminohydrolase activity and the metabolism of asymmetric dimethylarginine. [PDF]
Background— Experimental evidence suggests that estrogens stimulate the production of nitric oxide (NO) by vascular endothelial cells. This effect has been attributed to increased expression and enzymatic activity of both the constitutive and inducible ...
Cartwright, JE +7 more
core +1 more source
Shereshevsky-Turner syndrome: Estrogen replacement therapy and cardiovascular risk factors [PDF]
Aim. To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT ...
O A Yevstigneeva +5 more
doaj +1 more source
Malignancies Associated with Extraovarian Endometriosis: A Literature Review
Endometriosis-associated ovarian malignancies have been well documented. Although these malignancies also occur as extraovarian lesions, little is known about them. Thus, this literature review aimed to further explore these rarely experienced tumors.
Naoki Inoue +4 more
doaj +1 more source
Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions [PDF]
Background: Lower blood cholesterol concentrations have consistently been found to be strongly associated with lower risks of coronary disease but not with lower risks of stroke.
Heart Protection Study Collaborative Group +10 more
core +1 more source

