Results 11 to 20 of about 50,421 (294)

The Women's international study of long-duration oestrogen after menopause (WISDOM): a randomised controlled trial [PDF]

open access: yes, 2007
Background: At the time of feasibility work and final design of the trial there was no randomised control trial evidence for the long-term risks and benefits of hormone replacement therapy.
Knott, C.   +31 more
core   +1 more source

Hormone replacement therapy is associated with improved verbal declarative memory in healthy relatively recent postmenopausal women. [PDF]

open access: yes, 2006
The efficacy of Hormone Replacement Therapy (HRT) for cognitive health in postmenopausal women has been systematically questioned during the last decade.
Sünram-Lea, Sandra I.   +3 more
core   +1 more source

Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. [PDF]

open access: yes, 2004
This chapter about antithrombotic therapy for coronary artery disease (CAD) is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do,
Christopher M. O'Connor   +13 more
core   +1 more source

WISDOM: history and early demise - was it inevitable? [PDF]

open access: yes, 2002
In 1989, the UK Medical Research Council (MRC) agreed that, if feasible, a randomized controlled trial to assess the long-term risks and benefits of hormone replacement therapy (HRT) was a priority.
Darbyshire, J, Meade, T, Vickers, M
core   +1 more source

HORMONAL TREATMENT IN UROGYNECOLOGY

open access: yesZdravniški Vestnik, 2018
Background. Hormonal treatment in urogynecology is based on the knowledge, that urinary and reproductive tracts have common embriologic origin and are also linked anatomically and functionally.
Adolf Lukanović
doaj   +1 more source

Skin ageing [PDF]

open access: yes, 2007
Cutaneous ageing manifests itself as a progressive reduction in maximum function and reserve capacity of skin tissue. It is not a unique and uniform biological event. Skin comprises three layers: epidermis, dermis and subcutaneous tissue.
Brincat, Mark P.   +2 more
core   +1 more source

Effect of estrogen receptor-alpha (ESR1) gene polymorphism on high density lipoprotein levels in response to hormone replacement therapy

open access: yesBrazilian Journal of Medical and Biological Research, 2009
Studies have shown that estrogen replacement therapy and estrogen plus progestin replacement therapy alter serum levels of total, LDL and HDL cholesterol levels.
N.C. Nogueira-de-Souza   +6 more
doaj   +1 more source

Inhibition of Rho kinase mediates the neuroprotective effects of estrogen in the MPTP model of Parkinson's disease

open access: yesNeurobiology of Disease, 2013
The mechanism by which estrogen protects dopaminergic neurons has not yet been clarified. It is not known if changes in RhoA/Rho kinase activity are involved in the enhanced vulnerability of dopaminergic neurons observed after estrogen depletion.
Ana I. Rodriguez-Perez   +4 more
doaj   +1 more source

Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy

open access: yesCase Reports in Cardiology, 2012
Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use.
Alexander L. Pan   +3 more
doaj   +1 more source

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