Study of Immobilization Procedure on Silver Nanolayers and Detection of Estrone with Diverged Beam Surface Plasmon Resonance (SPR) Imaging [PDF]
Biosensors, 2013 An immobilization protocol was developed to attach receptors on smooth silver thin films. Dense and packed 11-mercaptoundecanoic acid (11-MUA) was used to avoid uncontrolled sulfidization and harmful oxidation of silver nanolayers.
Ibrahim Abdulhalim +3 more
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The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells. [PDF]
PLoS ONE, 2012 Estrone and estradiol are both estrogens with estrone being the less potent form and estradiol being the most potent estrogen. The binding of the latter to cellular regulatory elements stimulates the proliferation of breast cancer cells.
Chen-Yan Zhang +3 more
doaj +2 more sources
A Receptor-Independent Effect of Estrone Sulfate on the hERG Channel
Journal of Pharmacological Sciences, 2009 We recently reported that physiological concentrations of 17β-estradiol partially down-regulate cardiac rapidly-activating delayed rectifier K+ currents (hERG currents) independently of estrogen-receptor signaling.
Shoko Kakusaka +6 more
doaj +3 more sources
The Scientific World Journal, 2012 Background. The link between endogenous estrogen, coronary artery disease (CAD), and death in postmenopausal women is uncertain. We analyzed the association between death and blood levels of estrone in postmenopausal women with known coronary artery ...
Antonio de Padua Mansur +7 more
doaj +2 more sources
A MALDI-MS-based quantitative analytical method for endogenous estrone in human breast cancer cells [PDF]
Scientific Reports, 2016 The level of endogenous estrone, one of the three major naturally occurring estrogens, has a significant correlation with the incidence of post-menopausal breast cancer.
Kyoung Jin Kim +11 more
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Sex and reproductive stage modify the effect of endogenous oestrogens on coronary atherosclerosis in rheumatoid arthritis [PDF]
RMD OpenObjective We explored associations between endogenous oestrogens, coronary atherosclerosis and cardiovascular risk in rheumatoid arthritis (RA). We interrogated whether these relationships varied by sex and menopause and reflected differences in ...
George Athanasios Karpouzas +6 more
doaj +2 more sources
TiO2-assisted photocatalytic degradation of diclofenac, metoprolol, estrone and chloramphenicol as endocrine disruptors in water [PDF]
Adsorption, 2013 The photocatalytic oxidation of diclofenac, metoprolol, estrone and chloramphenicol was tested in the tube reactor using different commercially available TiO2. The photocatalysts were characterized using BET, XRD and SEM.
Bożena Czech, Katarzyna Rubinowska
openalex +2 more sources
A Systematic Review of Estrogens as Emerging Contaminants in Water: A Global Overview Study from the One Health Perspective [PDF]
Journal of XenobioticsThe widespread presence of estrogens in aquatic environments represents a One Health concern, as it simultaneously threatens environmental integrity, wildlife health, and human well-being.
Rhitor Lorca da Silva +8 more
doaj +2 more sources
Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity [PDF]
Frontiers in PharmacologyIntroductionIncreased CYP3A-mediated drug clearance during pregnancy can lead to subtherapeutic dosing of CYP3A substrates. Pregnancy-related hormones (PRHs) increase CYP3A4 expression and activity in cultured human hepatocytes.
Muluneh M. Fashe +8 more
doaj +2 more sources
Urinary Glyphosate Concentrations and Serum Sex Hormones in a Nationally Representative U.S. Sample: NHANES 2017–2018 [PDF]
LifeGlyphosate and glyphosate-based herbicides (GBHS) are the most widely used herbicides worldwide, yet their potential endocrine-disrupting effects in humans remain inadequately studied.
Wen-Yang Wu +4 more
doaj +2 more sources