Results 61 to 70 of about 68,328 (223)

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. [PDF]

, 2019
Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects ...
Boerwinkle, Eric, Cheung, Kit Wun Kathy, Chien, Huan-Chieh, Feofanova, Elena V, Giacomini, Kathleen M, Irannejad, Roshanak, Kinchen, Jason M, Stecula, Adrian, Suhre, Karsten, van Borselen, Marjolein, Yee, Sook Wah, Yousri, Noha A, Yu, Bing, Zou, Ling   +13 more
core   +2 more sources

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

British Journal of Clinical Pharmacology, EarlyView.
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann, Julian Peter Müller, Stefan Düsterhöft, Sabrina Yamoune, Katja Susanne Just, Julia Carolin Stingl   +5 more
wiley   +1 more source

$\Delta ^{9,11}$-Estrone derivatives as potential antiproliferative agents: synthesis, in vitro biological evaluation and docking studies

Comptes Rendus. Chimie, 2020
A series of ${\Delta }^{{9,11}}$-estrone derivatives with A- and D-ring modifications has been synthesized and evaluated as antiproliferative agents. The cytotoxicity was assessed in six cell lines (MCF-7, T47-D, LNCaP, HepaRG, Caco-2 and NHDF) by the 3-(
Canário, Catarina, Matias, Mariana, de Brito, Vanessa, Santos, Adriana O., Falcão, Amílcar, Silvestre, Samuel, Alves, Gilberto   +6 more
doaj   +1 more source

Dibenzo[a,g]quinolizin-8-ones: synthesis, estrogen receptor affinities, and cytostatic activity [PDF]

, 1992
A number of acetoxy-substituted dibenzo[a,g]quinolizin-8-ones were synthesized by the reaction of 1-oxoisoquinolines with substituted homophthalic acid anhydride.
Angerer, S. von, Brandl, G., Mannschreck, Albrecht, Weimar, C., Wiegrebe, Wolfgang   +4 more
core  

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

A Sulfuryl Group Transfer Strategy to Selectively Prepare Sulfated Steroids and Isotopically Labelled Derivatives

Frontiers in Molecular Biosciences, 2021
The treatment of common steroids: estrone, estradiol, cortisol, and pregnenolone with tributylsulfoammonium betaine (TBSAB) provides a convenient chemoselective conversion of the steroids alcohol/phenol moiety to the corresponding steroidal organosulfate.
Jaber A. Alshehri, Daniel M. Gill, Alan M. Jones   +2 more
doaj   +1 more source

Palladium-catalyzed acetylation of arenes. [PDF]

, 2014
A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in ...
Garg, Neil K, Ramgren, Stephen D
core   +1 more source

Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization

ChemistryEurope, EarlyView.
A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo, Jing Dai, Yongchang Wei, Chang Min   +3 more
wiley   +1 more source

Separation and lipophilicity of some new steroid derivatives in normal- and reversed-phase high performance liquid chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2011
The separation ability and retention of normal and reversed phase HPLC with, respectively, three non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized estrone derivatives.
Ačanski Marijana M., Vujuć Đura N., Jovanović-Šanta Suzana   +2 more
doaj   +1 more source