Results 41 to 50 of about 1,575,772 (344)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Theoretical estimation of the environmental impact of biofuel mixtures

Transport, 2009
Vehicles are burning fuels inefficiently. Nowadays, there is a strong correlation between CO2 emission and climate change. The article estimates a theoretical environmental impact of biofuel mixtures on the transport sector.
Ádám Török
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The calcineurin-responsive transcription factor Crz1 regulates the expression of CMK2 via a sole CDRE site in its promoter in budding yeast

Scientific Reports
As a yeast homolog of mammalian calcium/calmodulin-dependent protein kinase II (CaMKII), Cmk2 functions as a negative regulator of calcium signaling in Saccharomyces cerevisiae.
Linghuo Jiang, Yiying Gu, Yongqiang Jiang, Liudan Wei, Lijun Meng, Ni Guan   +5 more
doaj   +1 more source

Can Hawaii Meet Its Renewable Fuel Target? Case Study of Banagrass-Based Cellulosic Ethanol

ISPRS International Journal of Geo-Information, 2016
Banagrass is a biomass crop candidate for ethanol production in the State of Hawaii. This study examines: (i) whether enough banagrass can be produced to meet Hawaii’s renewable fuel target of 20% highway fuel demand produced with renewable sources by ...
Chinh Tran, John Yanagida
doaj   +1 more source

About solvents used in the preparation of oils for cosmetic products complying with the Cosmos standard☆

Oilseeds and fats, crops and lipids, 2021
Solvents have a bad reputation in the cosmetics world, at least as regards the production of specialty vegetable oils used in this market. In order to do without these solvents, the cosmetics industry tends to use only mechanically produced oils. However,
Carré Patrick
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Effects of different surface treatments on bond strength of an indirect composite to bovine dentin

Indian Journal of Dental Research, 2015
Background: Several surface treatments could be used to improve the bond strength (BS) between indirect composites and cement. Aim: To evaluate the BS of an indirect composite submitted to different surface treatments, cemented to bovine dentin. Settings
Laiza Tatiana Poskus, Rosana Sampaio Meirelles, Victor Blunck Schuina, Liana Matos Ferreira, Eduardo Moreira da Silva, Jose Guilherme Antunes Guimarães   +5 more
doaj   +1 more source

Honey Mead Fermentation from Thai Stingless Bee (Tetragonula leaviceps) Honey using Ethanol Tolerant Yeast

Kvasný průmysl, 2021
Honey mead is a well-known conventional alcoholic beverage made by microbial fermentation of diluted honey. The selection of prospective yeasts for inoculation of honey-must with regard to honey mead quality determines the quality of mead production. The
Pimprapa Chaijak, Purimprach Sinkan, Santipap Sotha   +2 more
doaj   +1 more source

Dimers of Ethanol

The Journal of Physical Chemistry A, 2004
The energy difference between the gauche and trans structures of ethanol is determined at the CCSD(T)/aug-cc-pVTZ level. Five classes of dimer structures exist due to the two monomer conformations. In a systematic way 600 structures were generated as initial structures for the dimer geometry optimization.
openaire   +3 more sources