Results 51 to 60 of about 1,575,772 (344)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study

Frontiers in Behavioral Neuroscience, 2019
Recent animal models of alcohol use disorder (AUD) are centered in capturing individual vulnerability differences in disease progression. Here, we used genetically selected Marchigian Sardinian alcohol-preferring (msP) and Wistars rats to apply a ...
Ana Domi, Serena Stopponi, Esi Domi, Roberto Ciccocioppo, Nazzareno Cannella   +4 more
doaj   +1 more source

Ammonia/Ethanol Mixture for Adsorption Refrigeration

Energies, 2020
Adsorption refrigeration has become an attractive technology due to the capability to exploit low-grade thermal energy for cooling power generation and the use of environmentally friendly refrigerants.
Mauro Luberti, Chiara Di Santis, Giulio Santori   +2 more
doaj   +1 more source

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role

Frontiers in Pharmacology, 2021
Background: In the current study, we evaluated the therapeutic potential of sinapic acid (SA) in terms of the mechanism underlying its gastroprotective action against ethanol-induced gastric ulcers in rats.Methods: These effects were examined through ...
Mohammad Raish, Mudassar Shahid, Yousef A. Bin Jardan, Mushtaq Ahmad Ansari, Khalid M. Alkharfy, Abdul Ahad, Ibrahim Abdelsalam Abdelrahman, Ajaz Ahmad, Fahad I. Al-Jenoobi   +8 more
doaj   +1 more source

Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-κB Signaling Pathways in Mice

Oxidative Medicine and Cellular Longevity, 2018
Taraxasterol, a pentacyclic-triterpene compound, is one of the main active components isolated from the traditional Chinese medicinal herb Taraxacum.
Lu Xu, Yifan Yu, Rui Sang, Jinxia Li, Bingjie Ge, Xuemei Zhang   +5 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Aditivos químicos e biológicos na ensilagem de cana-de-açúcar: 1. composição química das silagens, ingestão, digestibilidade e comportamento ingestivo Chemical and biological additives in the ensiling of sugar cane: 1. chemical composition, dry matter intake, digestibility and ingestive behavior

Revista Brasileira de Zootecnia, 2007
Avaliou-se o efeito da inclusão de aditivos na ensilagem de cana-de-açúcar (Saccharum officinarum L.) sobre a composição químico-bromatológica das silagens, o comportamento ingestivo, o consumo voluntário e a digestibilidade em bovinos de corte ...
Patrick Schmidt, Lucas José Mari, Luiz Gustavo Nussio, André de Faria Pedroso, Solidete de Fátima Paziani, Francisco Stefano Wechsler   +5 more
doaj   +1 more source

Effects of Ethanol Exposure During Adolescence or Adulthood on Locomotor Sensitization and Dopamine Levels in the Reward System

Frontiers in Behavioral Neuroscience, 2020
Behavioral sensitization is a process of neuroadaptation characterized by a gradual increase in motor behaviors. The major neural substrates involved in the behavioral sensitization lie on the dopaminergic mesocorticolimbic pathway, which is still under ...
Priscila Fernandes Carrara-Nascimento, Lucas Barbosa Hoffmann, Jorge Camilo Flório, Cleopatra Silva Planeta, Rosana Camarini   +4 more
doaj   +1 more source

Rutin inhibits DRP1-mediated mitochondrial fission and prevents ethanol-induced hepatotoxicity in HepG2 cells and zebrafish

Animal Cells and Systems, 2021
Excessive alcohol consumption causes the cellular and tissue damage. The toxic metabolites of ethanol are harmful to multiple organ systems, such as the central nervous system, skeletal muscles, and liver, and cause alcohol-induced diseases like cancer ...
Youngsook Choi, Heymin Seo, Mina Cho, Joohee Kim, Hak Suk Chung, Icksoo Lee, Min Jung Kim   +6 more
doaj   +1 more source

Techno-economic evaluation of integrated first- and second-generation ethanol production from grain and straw

Biotechnology for Biofuels, 2016
BackgroundIntegration of first- and second-generation ethanol production can facilitate the introduction of second-generation lignocellulosic ethanol production.
Elisabeth Joelsson, Borbála Erdei, M. Galbe, Ola Wallberg   +3 more
semanticscholar   +1 more source