Results 51 to 60 of about 1,177,692 (316)

Advances in Relationship Between Alcohol Consumption and Skin Diseases

Clinical, Cosmetic and Investigational Dermatology, 2023
Lin Liu, Jin Chen Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Jin Chen, Department of Dermatology, The First Affiliated Hospital of Chongqing Medical ...
Liu L, Chen J
doaj  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Efecto de diámetro de esfera y densidad celular en la producción de etanol con levadura inmovilizada en alginato

Revista Colombiana de Biotecnología, 2011
Effect of pellet diameter and cell density on ethanol production with alginate immobilized yeast Título corto: Producción de etanol con levadura inmovilizada ResumenLas células inmovilizadas tienen aplicación potencial en la producción de biocombustibles
Martha V. Jiménez, Gabriella G. Zarkovic, Gretty K. Villena, Marcel Gutiérrez-Correa   +3 more
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Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Pengaruh prosentase etanol terhadap daya dan konsumsi bahan bakar mesin pembakaran busi

Jurnal Energi Dan Manufaktur, 2017
Abstrak: Penelitian ini merupakan studi eksperimental pengaruh penambahan etanol terhadap kinerja mesin pembakaran busi (mesinbensin), meliputi daya efektif dan konsumsi bahan bakar spesifiknya.
Mega Nur Sasongko
doaj  

Aplicação da metodologia de planejamento fatorial e análise de superfícies de resposta para otimização da fermentação alcoólica Application of the factorial design and response surface methodology for optimization of alcoholic fermentation

Química Nova, 2008
In the present work, the influence of the amount of nitrogen and phosphorus and degrees Brix on the yield and productivity of alcoholic fermentation has been evaluated. The methodology used was factorial design and response surface analysis.
José Alexsandro Silva, Bolívar Ponciano Goulart de Lima Damasceno, Flávio Luiz Honorato da Silva, Marta Suely Madruga, Davi Pereira de Santana   +4 more
doaj   +1 more source

High-Fat Diet Induced Alteration of Mice Microbiota and the Functional Ability to Utilize Fructooligosaccharide for Ethanol Production

Frontiers in Cellular and Infection Microbiology, 2020
High-fat diet (HFD) leads to enhancement in various parameters of mice like weight, fasting glucose levels, adipose tissue, and also the liver weight in male C57 BL/6 J mice.
Rajnish Prakash Singh, Diana Abu Halaka, Zvi Hayouka, Oren Tirosh   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source