Results 121 to 130 of about 22,847 (294)

Advances in Chlorinated Polyethylene: Properties, Applications, and Future Directions

Journal of Applied Polymer Science, EarlyView.
This work highlights recent advances in the synthesis of chlorinated polyethylene (CPE), its versatile industrial applications, and emerging innovations driving its future development in sustainable materials. ABSTRACT Elastomeric chlorinated polyethylene (CM or E‐CPE) integrates the thermoplastic's dynamic processing properties with the elastomer's ...
J. I. Mnyango, L. L. Bolo, B. G. Fouda‐Mbanga, Z. Tywabi‐Ngeva, Y. B. Nthwane, K. Pillay, P. P. Ndibewu, S. P. Hlangothi   +7 more
wiley   +1 more source

Evaluation of cardiac arrhythmia incidence in patients treated with oral moxifloxacin

International Journal of the Cardiovascular Academy, 2019
Background: The effect of moxifloxacin on QT interval is reversible and dose related, mainly provided by weakly but rapidly activated rectifying potassium channel blockade, IKr or human ether-a-go-go-related gene potassium channels.
Casit Olgun Celik, Aylin Yıldırır, Kaan Okyay, İlyas Atar, Mehmet Bülent Özin, İbrahim Haldun Müderrisoğlu   +5 more
doaj   +1 more source

Gain of function mutants: Ion channels and G protein-coupled receptors [PDF]

, 2000
Many ion channels and receptors display striking phenotypes for gain-of-function mutations but milder phenotypes for null mutations. Gain of molecular function can have several mechanistic bases: selectivity changes, gating changes including constitutive
Karschin, Andreas, Lester, Henry A.
core   +1 more source

Impact of Advances in Anion Exchange Membranes and Ionomers on Alkaline Fuel Cells

Chemistry – An Asian Journal, EarlyView.
Advances in anion exchange membranes (AEMs) and ionomer design have propelled alkaline fuel cells toward unprecedented performance, with peak power densities exceeding 3.5 W cm⁻2. This review highlights how molecular‐level innovations— stable hydrocarbon backbones, robust cationic groups, and pH‐gradient‐enabled bipolar interfaces—enable durable, high ...
Zhongyang Wang, Shrihari Sankarasubramanian, Jianping Chen, Vijay K. Ramani   +3 more
wiley   +1 more source

In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome

Frontiers in Physiology, 2019
Short QT syndrome variant 1 (SQT1) arises due to gain-of-function mutations to the human Ether-à-go-go-Related Gene (hERG), which encodes the α subunit of channels carrying rapid delayed rectifier potassium current, IKr.
Dominic G. Whittaker, Dominic G. Whittaker, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang, Henggui Zhang   +7 more
doaj   +1 more source

Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms

, 2010
The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified.
Gong, Qiuming, Stump, Matthew R., Dunn, A. Russell, Deng, Vivianne, Zhou, Zhengfeng   +4 more
core  

Group IVA Alloy Anodes for Sodium‐Ion Rechargeable Batteries: Electrochemistry, Mechanics, and Kinetics

Batteries &Supercaps, EarlyView.
Anode choices for sodium‐ion batteries remain limited. This review explores Group IVA alloy elements (Si, Ge, Sn, Pb) as anodes, focusing on their electrochemistry, mechanical behavior, and kinetic properties. By analyzing their Na storage mechanisms and challenges, this work provides insights and future directions for advancing sodium‐ion battery ...
Jia Zhang, Tianye Zheng
wiley   +1 more source

In vitro chronic effects on hERG channel caused by the marine biotoxin Yessotoxin.

Frontiers in Marine Science, 2014
INTRODUCTION Marine algal blooms caused by the overgrowth of marine phytoplankton have increased in frequency and severity in the last years; supposing a worldwide public health problem.
Sara Fernández Ferreiro
doaj   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

BMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang, Yefei Dai, Yujun Hou, Joshua Stein, Shichen Steven Lin, Chaochen Zhou, Yannan Hou, Rongrong Zhu, Ki‐Bum Lee, Letao Yang   +9 more
wiley   +1 more source

Electrophysiological characterization of a small molecule activator on human ether-a-go-go-related gene (hERG) potassium channel

Journal of Pharmacological Sciences, 2019
The human ether-a-go-go-related gene (hERG) encodes the K+ channel that carries the rapid component of the delayed rectifier current in the human heart. Reduction of hERG activity induced by gene mutations or pharmacological inhibition is responsible for the type 2 form of long QT syndrome in patients which can develop into ventricular arrhythmia and ...
Gongxin Wang, Heling Niu, Liying Dong, Xiuming Dong, Yani Liu, KeWei Wang, An-ruo Zou   +6 more
openaire   +4 more sources