The molecular basis of KCNH1-related epileptic encephalopathy and the challenge of developing targeted therapeutics. [PDF]
Sundman AK, Jin S, Vadlamudi L, King GF.
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Quantification of Human Cardiac Ion Channels by Parallel Reaction Monitoring and In-Sample Calibration. [PDF]
Torkamannejad S, Yip HY, Sun B.
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The mechanism of electrical remodeling in atrial fibrillation and current research status of natural drugs and active ingredients inhibiting atrial electrical remodeling. [PDF]
Huang X +7 more
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Gating modulation and potentiation of amiodarone blockage of the Kv10.1 potassium channel bu KB130015, an amiodarone derived molecule. [PDF]
Gómez-Lagunas F, Barriga-Montoya C.
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The Potential Role of Verapamil Against Fluconazole-Induced Torsade de Pointes: A Critical Review. [PDF]
Abdel-Razik NE +7 more
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Loss of Potassium and Chloride Transport Changes PM-Induced Epithelial Dysfunction. [PDF]
Jaworowska S +5 more
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QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]
Gotta V, Donner B.
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Cardiovascular adverse effects of common non-oncologic medications: from mechanisms to clinical management. [PDF]
Bahit MC +3 more
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Ether à go-go potassium channels and cancer
Cancer Letters, 2006Ion channels play important roles in health and disease. In the last few years, an interesting relationship between potassium channels and cancer has evolved. Especially, members of the ether à go-go (EAG) potassium channels family have gained interest as research tools for detection and therapy of different cancers.
Javier Camacho
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Expression of ether à go-go potassium channels in human gliomas
Neuroscience Letters, 2004Ether à go-go (EAG) K(+) channels have been shown to be involved in tumor generation and malignant growth. Gliomas have not been investigated thus far. Using RT-PCR we investigated healthy human brain and human gliomas of different subtypes and malignancy grades for the expression of human EAG1 and eag-related gene (ERG) 1 channels.
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