Results 151 to 160 of about 22,847 (294)

Enhanced Electroactivity for Overall Water Splitting and Oxygen Potential of Pt/Carbon Nanotubes Functionalized with Cu Organometallic Complex

Energy Technology, EarlyView.
Functionalizing carbon nanotubes (CNT) with the mesitylcopper (Cu‐mes) complex modifies the surface of CNT, developing Cu‐Pt alloys and Cu‐species. The result is a modified Pt electronic structure that promotes the catalytic activity of the 5 wt% Pt/CNTCu‐mes nanocatalyst for hydrogen and oxygen evolution reactions, and oxygen reduction reaction.
Rocio López‐Leal, Manuel Octavio Fuentez‐Torres, María Esther Sánchez‐Castro, Ivonne L. Alonso‐Lemus, Beatriz Escobar‐Morales, Javier Rodríguez‐Varela   +5 more
wiley   +1 more source

Inhibition of Nonsense-Mediated mRNA Decay by Antisense Morpholino Oligonucleotides Restores Functional Expression of hERG Nonsense and Frameshift Mutations in Long-QT Syndrome

, 2010
Mutations in the human ether-a-go-go-related gene (hERG) cause long-QT syndrome type 2 (LQT2). We previously described a homozygous LQT2 nonsense mutation Q1070X in which the mutant mRNA is degraded by nonsense-mediated mRNA decay (NMD) leading to a ...
Bhuiyan, Bhuiyan, Conti, Curran, Dominski, Friedman, Frischmeyer, Gong, Gong, Gritz, Holbrook, Howard, Jearawiriyapaisarn, Kapplinger, Khajavi, Kuzmiak, Le Hir, Le Roy, Linde, Lykke-Andersen, Matthew R. Stump, Millat, Nagy, Napolitano, Nicholson, Qiuming Gong, Sanguinetti, Schwartz, Shimizu, Splawski, Stalder, Tester, Trudeau, Usuki, Wu, Yao, Zhang, Zhengfeng Zhou, Zhou, Zhou   +39 more
core   +1 more source

Distinguishing Rock Fracture and Pore's T2 Signals From NMR Experiments With Assisted X‐Ray CT Imaging

Energy Science &Engineering, EarlyView.
ABSTRACT Nuclear magnetic resonance (NMR) is widely used to characterize fluids in rock pore spaces, but traditional methods have difficulty distinguishing fractures from matrix pores in complex carbonate formations. To address this, we developed a calibration method that integrates X‐ray computed tomography (CT) imaging with NMR to identify fracture ...
Ying Yang, Limin Li, Tingjun Wen, Luyi W. Shen, Elton J. Chen, Xu Dong, Jiangen Xu   +6 more
wiley   +1 more source

Assessment of the Effects of Fruquintinib on Cardiac Safety in Patients with Metastatic Colorectal Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib is a highly selective oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, approved by the US Food and Drug Administration and the European Commission for the treatment of previously treated metastatic colorectal cancer (mCRC), regardless of biomarker status. This study used concentration QT interval (C‐QTc)
Xiaofei Zhou, Alice Toms, Dave Morton, Xiaohui Wang, Adekemi Taylor, Arvind Dasari, Neeraj Gupta, Caly Chien   +7 more
wiley   +1 more source

The Human Ether-a-go-go-related Gene (hERG) Potassium Channel Represents an Unusual Target for Protease-mediated Damage [PDF]

, 2016
Shawn M. Lamothe, Guo Jun Liu, Wentao Li, Tonghua Yang, Shetuan Zhang   +4 more
openalex   +1 more source

Recent advances in our understanding of the structure and function of more unusual cation channels. [PDF]

, 2019
As their name implies, cation channels allow the regulated flow of cations such as sodium, potassium, calcium, and magnesium across cellular and intracellular membranes.
Brown, Brandon M, Nguyen, Hai M, Wulff, Heike   +2 more
core   +1 more source

Microfluidic Synthesis of Hyaluronic Acid Microgels in a Coaxial Flow Reactor

Macromolecular Materials and Engineering, EarlyView.
A coaxial flow reactor allows continuous production of hyaluronic microgels with efficient parameter optimisation through Design‐of‐Experiments. ABSTRACT Microgels combine the strengths of hydrogels and microparticles. The multiple advantages of microgels, including control of drug release, excellent loading efficiency, high stability, and ...
Shuting Li, Xinyuan Jia, Duncan Q. M. Craig, Rachael Dickman, Michael T. Cook   +4 more
wiley   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, EarlyView.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Investigating the threat to Sitka spruce from Ips typographus: discrimination and colonization of Britain's principal commercial conifer by a damaging forest pest

Pest Management Science, EarlyView.
The forest pest Ips typographus was found to demonstrate attraction to Sitka spruce, and to colonize and breed upon cut logs as successfully as its primary host Norway spruce. This has implications for the beetle's establishment and impact in Sitka‐growing regions, including Britain where I.
Daegan Inward, Jozsef Vuts, Gareth Thomas, Kerry Barnard, John C. Caulfield, Stephen J. Powers, Ana Uglow, Katy Reed   +7 more
wiley   +1 more source

Regulation of Kv11.1 Potassium Channel C-Terminal Isoform Expression by the RNA-Binding Proteins HuR and HuD

, 2018
The potassium voltage-gated channel subfamily H member 2 (KCNH2) gene encodes the Kv11.1 potassium channel, which conducts the rapidly activating delayed rectifier current in the heart.
Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng   +2 more
core