Results 91 to 100 of about 13,577,124 (238)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Survey on Ethical Knowledge and Research Implementation Compliance Among Clinical Researchers

Yixue yu zhexue
To assess the ethical knowledge level of clinical researchers, the ethical compliance during research implementation, and the difficulties and confusions encountered in conducting studies and ethical reviews, an online self-administered questionnaire ...
Jianan FENG, Shanshan HUANG, Chuanzhou YANG, Xiaopin WANG, Jie QIAO   +4 more
doaj   +1 more source

Artificial intelligence and medical research databases: ethical review by data access committees. [PDF]

BMC Med Ethics, 2023
McKay F, Williams BJ, Prestwich G, Bansal D, Treanor D, Hallowell N.   +5 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The Supreme Bioethics Committee in the new clinical trial ethics assessment system. Comments de lege ferenda and de lege lata

Journal of Modern Science
The aim of this article is to present the issues concerning the role and constitutional position of the Supreme Bioethics Commission in the system of ethical evaluation of clinical trials in Poland.
Monika Urbaniak
doaj   +1 more source

A narrative review on the development of the ethical review mode of multicenter clinical trials in China. [PDF]

Ann Transl Med, 2022
Ding J, Yin Y, Fang K, Zhang W, Luo S.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Should social science and the humanities have to undergo ethical review? [Elektronisk resurs] : A normative assessment of four common arguments

In Sweden, as well as in many other countries, it is customary that at least some human subject research must undergo ethical review and receive an ethical approval before it may begin (Johansson et al. 2023).
Persson, Vilhelm,, Bülow, William,, Johansson, Mats,, Wahlberg, Lena,   +3 more
core  

Ethical Review Challenges and Practices of Brain-Computer Interfaces Research in Psychiatry

Yixue yu zhexue
In psychiatric research involving brain-computer interface (BCI) technologies, most participants are individuals with severe, treatment-resistant conditions, whose urgent desire for relief may compromise their decision-making capacity.
Li LI, Lingling YE, Weimin YANG
doaj   +1 more source

Ethical review of off-label drugs during the COVID-19 pandemic. [PDF]

World J Clin Cases, 2022
Li QY, Lv Y, An ZY, Dai NN, Hong X, Zhang Y, Liang LJ.   +6 more
europepmc   +1 more source