Results 121 to 130 of about 13,577,124 (238)

Current Status and Issues of Ethical Review for Surgical Research in Japanese University Hospitals. [PDF]

JMA J, 2022
Doi M, Yukawa K, Sato H.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Systematic Review of the Ethical Considerations of Delivering Video-Based Therapy

Objective The use of video technology in synchronous psychotherapy has increased over the last few years, with a particularly rapid uptake following the onset of the global COVID-19 pandemic. This systematic review aims to provide an understanding of the
Webb, Xanthe, van Kessel, Kirsten, Du Preez, Elizabeth   +2 more
core   +1 more source

Ethical Review of Animal Research and the Standards of Procedural Justice: A European Perspective. [PDF]

J Bioeth Inq, 2021
Pietrzykowski T.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Ethical review of COVID-19 vaccination requirements for transplant center staff and patients. [PDF]

Am J Transplant, 2022
Kates OS, Stock PG, Ison MG, Allen RDM, Burra P, Jeong JC, Kute V, Muller E, Nino-Murcia A, Wang H, Wall A.   +10 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Purpose versus pragmatism: participant perspectives on the process of ethical review of animal research in Sweden

Frontiers in Animal Science
All EU research projects involving non-human animals must undergo prior project evaluation, also known as ethical review, to safeguard animal welfare.
Svea Jörgensen, Helena Röcklinsberg, Elin M. Weber, Clara Iversen, Frida Lundmark Hedman   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Establishment of the Certified Research Ethics Professionals: An Ethical Review Expert -Translated in English from Japanese Version. [PDF]

JMA J, 2021
Ebana Y, Yang SH, Yokono M, Yoshida M.
europepmc   +1 more source