Results 151 to 160 of about 12,286,533 (342)
In Sweden, as well as in many other countries, it is customary that at least some human subject research must undergo ethical review and receive an ethical approval before it may begin (Johansson et al. 2023).
Johansson, Mats +3 more
core +1 more source
Characterization of Factors Predicting a Favorable Opinion of Research Applications Submitted for an Ethical Review Process. [PDF]
Front Med (Lausanne), 2022 Mirpuri E +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Ethical marketing: a review and research agenda
Purpose – The paradigm-shifting era of automation, digitalization, hyper-connectivity, obligations, globalization and sustainability (ADHOGS) in the face of disruption, volatility, uncertainty, complexity, and ambiguity (DVUCA) has resulted in ...
Fandos, Juan Carlos +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2011 Melbourne VICGlobal initiatives for single ethical review for clinical trials Countries that have worked to adopt single ethics review for multisite clinical trials ...
Single Ethics Review +1 more
core
Tracing app technology: an ethical review in the COVID-19 era and directions for post-COVID-19. [PDF]
Ethics Inf Technol, 2022 Afroogh S +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
What are We Asking Patients to Do? A Critical Ethical Review of the Limits of Patient Self-Advocacy in the Oncology Setting. [PDF]
New Bioeth, 2023 Wilkenfeld DA, Hagan Thomas T.
europepmc +1 more source