Results 61 to 70 of about 1,513,082 (305)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
The philosophy of memory today and tomorrow: Editors' introduction [PDF]
, 2018 This introductory chapter provides an overview of the chapters making up the book, which are grouped into six sections: challenges and alternatives to the causal theory of memory; activity and passivity in remembering; the affective dimension of memory ...
Debus, Dorothea +2 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Ethics and Mind Theory in Stich's Philosophy; Moral Psychology and Cognitive Sciences United
Journal of Philosophical Investigations, 2014 Stephen Stich is one of the most outstanding psychologist and philosophers in the both ethics and mind fields. He merged psychological and philosophical traditions into one and became the source of many studies in moral psychology and philosophy of mind.
Mohammad Hadi Fazeli +1 more
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Critical Practice Leadership in Post-compulsory Education [PDF]
, 2013 This article questions why leaders in post-compulsory education tend not to view leadership research positively or utilise it in improving their practice.
Elliott, Geoffrey
core +4 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Ayn Rand’s Egoism: Theory and Analysis [PDF]
Religious Inquiries, 2015 Ayn Rand was a Russian-born American philosopher, novelist, and playwright, whose interpretation of ethical egoism is one of the most important interpretations of this theory.
Raham Sharaf +1 more
doaj
Intending to be ethical: An examination of consumer choice in sweatshop avoidance [PDF]
, 2007 While much research in ethical consumption has focused on contexts such as food, this research explores ethical consumer decision-making in the context of intention to avoid sweatshop apparel.
Bekin, C +4 more
core +1 more source
Ethics Beyond Moral Theory [PDF]
Philosophical Investigations, 2009 AbstractI develop an anti‐theory view of ethics. Moral theory (Kantian, utilitarian, virtue ethical, etc.) is the dominant approach to ethics among academic philosophers. But moral theory's hunt for a single Master Factor (utility, universalisability, virtue . . .) is implausibly systematising and reductionist.
openaire +1 more source