Results 91 to 100 of about 23,286,365 (332)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Symposium on Revenue Transparency, Resource Development, and the Challenge of Corruption [PDF]

open access: yes
Revenue transparency and corruption in the mining industry have long been topics of national and international conversation. Mining plays an important role in the Canadian economy, contributing billions to Canada’s GDP.
Canadian Business Ethics Research Network (CBERN)
core  

The Underrepresentation of Women in Prestigious Ethics Journals [PDF]

open access: yes, 2017
It has been widely reported that women are underrepresented in academic philosophy as faculty and students. This article investigates whether this representation may also occur in the domain of journal article publishing.
Dalecki, Maggie   +3 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Ethics – research, engineering, design… they’re all the same aren’t they? [PDF]

open access: yes, 2014
This paper considers how and to what extent product design ethics is understood by professionals in design practice and undergraduate students of product and engineering design and how, if at all, design ethics differ from engineering and/or research ...
Blount, G.   +2 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Reasons for resubmission of research projects to the research ethics committee of a University Hospital in São Paulo, Brazil

open access: yesClinics, 2009
INTRODUCTION: It is important to know the reasons for resubmitting research projects to the Research Ethics Committee in order to help researchers to prepare their research projects, informed consent forms and needed research documentation.
Mariana Bueno   +5 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Survey on the current practice of research ethics committees in the Czech academic environment: a mixed-methods study

open access: yesBMC Medical Ethics
Background The primary objective of this study was to conduct a comprehensive questionnaire survey on the practices of research ethics committees reviewing academic research projects in Czechia.
Renata Veselska, Jan Sirucek, Josef Kure
doaj   +1 more source

Observer l’éthique en train de se faire pour une approche pragmatique des commissions d’éthique de la recherche

open access: yesRevue d'anthropologie des connaissances, 2019
Research ethics commissions (REC) concentrate a large part of the debates on research ethics. However, few ethnographic inquires have been carried out to investigate their work.
Solène Gouilhers, Loïc Riom
doaj   +1 more source

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