Results 101 to 110 of about 860,404 (335)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Qualitative Research in Sport Sciences: Is the Biomedical Ethics Model Applicable?
Forum: Qualitative Social Research, 2003 Research in sports science has historically been grounded in positivist traditions. This means that ethics committees may not be adequately sensitized to the ethical problems posed by qualitative research.
Steve Olivier, Lesley Fishwick
doaj
Ethnographic Intimacy: Thinking Through the Ethics of Social Research in Sex Worlds [PDF]
Ethnographic researchers entering sensitive fields of research become entangled in ethical dilemmas when they encounter \'sticky\' questions, situations and issues.
Maria P�rez-y-P�rez, Tony Stanley
core
Ethical approval in developing countries is not optional [PDF]
, 2012 When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam, van Teijlingen, Edwin
core +1 more source
Co-design and implementation research: challenges and solutions for ethics committees
BMC Medical Ethics, 2015 BackgroundImplementation science research, especially when using participatory and co-design approaches, raises unique challenges for research ethics committees.
F. Goodyear-Smith +2 more
semanticscholar +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Revista BioéticaO comitê de ética em pesquisa tem como função revisar todas as pesquisas envolvendo seres humanos realizadas no Brasil, o que tem suscitado controvérsias sobre a revisão ética de pesquisas em ciências humanas e sociais. O objetivo deste artigo é discutir
Adriana Silva Barbosa +2 more
doaj +1 more source
Getting Beyond Form Filling: The Role of Institutional Governance in Human Research Ethics [PDF]
, 2018 It has become almost a truism to describe the interaction between research ethics committees and researchers as being marred by distrust and conflict.
Allen, Gary
core
Research ethics committees deserve support [PDF]
BMJ, 2005 I agree with Wade that audit and certain kinds of research have similarities in purpose, structure, and ethics and that audit is not reviewed within the same strict ethical guidelines.1 However, this does not indicate that “research and audit cannot be distinguished.” The definitions and differences have been published.2 3 Audit and research surveys ...
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source