Results 101 to 110 of about 478,794 (298)

Submission to Healthcare Ethics Committees in Portugal: Our Experience

Acta Médica Portuguesa
N/a.
Daniela Ribeiro, Carolina Sotana, Goranka Petriček, Joana Azeredo, Bruno Heleno   +4 more
doaj   +1 more source

Challenges in the ethics review process of clinical scientific research projects in China

Journal of International Medical Research, 2019
Purpose Ethics review processes have become increasingly complex. The objective of this study was to explore the challenges currently faced in ethics reviews of clinical scientific research projects in China, with the goal of standardizing the structure ...
Zhu-Heng Wang, Guan-Hua Zhou, Li-Ping Sun, Jun Gang   +3 more
doaj   +1 more source

Physical activity counselling in Ireland: a survey of doctors’ knowledge, attitudes and self-reported practice

BMJ Open Sport & Exercise Medicine, 2019
Objective Physical activity (PA) counselling has been shown to raise awareness of the importance of PA and to increase the rate of PA engagement among patients.
Lucia Prihodova, Sarah O'Brien, Mairéad Heffron, Peter Wright   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Research Ethics Committees (RECs) and the Creaking Piers of Peer Review [PDF]

[No abstract][No keywords]
John Holmwood
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Can an ethics officer role reduce delays in research ethics approval? A mixed-method evaluation of an improvement project. [PDF]

, 2016
OBJECTIVE: Frustration continues to be directed at delays in gaining approvals for undertaking health research in the UK. We aimed to evaluate the impact of an ethics officer intervention on rates of favourable opinions (approval) and provisional ...
Al-Shahi Salman, Rustam, Dixon-Woods, Mary, Foy, Chris, Hayden, Charlotte, Schroter, Sara, Tebbutt, Stephen   +5 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Evaluating research ethics committees in Vietnam and Laos: Results of a validated self-assessment tool.

PLoS ONE
BackgroundThere is an increase in human subject research in developing countries and conducting them in an ethical manner depends on the research ethics oversight in these countries.
Nathan Gabriel Sattah, Vincent D'Anniballe, Hoang Tu Le, Luyen Thi Le, Thanh Ngoc Le, Thom Thi Vu, Viengsakhone Louangpradith, Walter T Lee   +7 more
doaj   +1 more source