Results 121 to 130 of about 866,840 (339)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Conhecimento e envolvimento de graduandos em fisioterapia acerca dos preceitos éticos da experimentação animal

Revista Bioética
O artigo analisa em amostra de universitários do curso de fisioterapia indicadores éticos ao uso de animais na pesquisa e no ensino e o nível de conhecimento e interesse dos alunos sobre o tema ética animal.
Igor Fagioli Bordello Masson, Cristiano Schiavinato Baldan, Vanessa Reimberg Ramalho, Ivaldo Esteves Junior, Daniela Fagioli Masson, Beatriz de Oliveira Peixoto, Cassio Marcos Vilicev, Thiago Saikali Farcic   +7 more
doaj  

Research ethical committees and ethics dumping

Current Medicine Research and Practice, 2022
N A Uvais
doaj   +1 more source

Ethics Committees in Ayurvedic PG institutions: Losing opportunities of making an impact

Journal of Ayurveda and Integrative Medicine, 2018
Ethics is a crucial component of medical practice world over and also an indispensable part of medical research. Ethics in medical practice primarily refers to not harming the patients by the proposed interventions; similarly ethics in research refers to
Sanjeev Rastogi
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Challenges in the ethics review process of clinical scientific research projects in China

Journal of International Medical Research, 2019
Purpose Ethics review processes have become increasingly complex. The objective of this study was to explore the challenges currently faced in ethics reviews of clinical scientific research projects in China, with the goal of standardizing the structure ...
Zhu-Heng Wang, Guan-Hua Zhou, Li-Ping Sun, Jun Gang   +3 more
doaj   +1 more source

Can UK NHS research ethics committees effectively monitor publication and outcome reporting bias?

BMC Medical Ethics, 2015
BackgroundPublication and outcome reporting bias is often caused by researchers selectively choosing which scientific results and outcomes to publish.
Rasheda Begum, S. Kolstoe
semanticscholar   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Submission to Healthcare Ethics Committees in Portugal: Our Experience

Acta Médica Portuguesa
N/a.
Daniela Ribeiro, Carolina Sotana, Goranka Petriček, Joana Azeredo, Bruno Heleno   +4 more
doaj   +1 more source

A Clash of Paradigms? Ethnography and Ethics Approval

SAGE Open, 2017
Obtaining ethics approval from university ethics committees is an important part of the research process in Australia and internationally. However, for researchers engaging in ethnographic work, obtaining ethics approval can (re)present significant ...
Virginia Mapedzahama, Tinashe Dune
doaj   +1 more source