Results 41 to 50 of about 478,794 (298)

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Caracterização de protocolos de pesquisa: um estudo na Paraíba, Brasil

Revista Bioética
Resumo O artigo apresenta a caracterização da totalidade dos protocolos de pesquisa apreciados pelo Comitê de Ética em Pesquisa do Instituto Federal da Paraíba (CEP/IFPB), desde sua fundação, em 2008, até 2014. Trata-se de estudo descritivo e documental,
Genésio José da Silva, Maria Luiza da Costa Santos   +1 more
doaj   +1 more source

Ethics preparedness: facilitating ethics review during outbreaks - recommendations from an expert panel

BMC Medical Ethics, 2019
Background Ensuring that countries have adequate research capacities is essential for an effective and efficient response to infectious disease outbreaks.
Abha Saxena, Peter Horby, John Amuasi, Nic Aagaard, Johannes Köhler, Ehsan Shamsi Gooshki, Emmanuelle Denis, Andreas A. Reis, the ALERRT-WHO Workshop, Raffaella Ravinetto   +9 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

HREC members\u27 personal values influence decision making in contentious cases [PDF]

, 2017
This article identifies 14 contentious issues faced by Human Research Ethics Committees (HRECs). The authors argue that HREC members will respond variably to these issues based on their own fundamental values and worldview. In particular, we propose that
Brewer, Keagan, Fellman, Marc, Handal, Boris, Maher, Marguerite, Watson, Kevin   +4 more
core   +1 more source

Ethical issues in implementation research: a discussion of the problems in achieving informed consent [PDF]

, 2008
Background: Improved quality of care is a policy objective of health care systems around the world. Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinical practice ...
A Iversen, A Vahratian, American Statistical Association, B Briesacher, B Woodward, C Junghans, C Verity, Council of the International Organisation of Medical Sciences, D Raffe, H Ward, International Statistical Institute, J Grimshaw, J Tu, Jane L Hutton, Jeremy M Grimshaw, JL Hutton, JL Hutton, L Doyal, M Eccles, M Eccles, M Eccles, M Robling, M Thompson, Martin P Eccles, MP Eccles, MRC ethics series, R Baker, R Foy, R Grol, R Winkelmann, RE Ashcroft, RE Ashcroft, Royal Statistical Society, S Blackstone, S Rogerson, S Woolf, SJL Edwards, T Beauchap, T Walley, World Medical Association Declaration of Helsinki   +39 more
core   +3 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Analysis of ethics dumping and proposed solutions in the field of biomedical research in China

Frontiers in Pharmacology, 2023
As international academic exchanges and cooperation deepen, China has actively engaged in international biomedical research collaboration and achieved significant success.
Bohua Liao, Yonghui Ma, Ruipeng Lei, Ruipeng Lei   +3 more
doaj   +1 more source

Social and Communicative Functions of Informed Consent Forms in East Asia and Beyond [PDF]

, 2017
The recent research and technology development in medical genomics has raised new issues that are profoundly different from those encountered in traditional clinical research for which informed consent was developed.
Go, Yoshizawa, Ho, Chih Hsing, Kato, Kazuto, Sasongko, Teguh H.   +3 more
core   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn, Anna‐Lena Herbach, Christian Bock, Katharina Fleig, Urs Mücke   +4 more
wiley   +1 more source