Results 161 to 170 of about 2,047,734 (258)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Review of Ethics. [PDF]

Psychological Bulletin, 1909
openaire   +1 more source

Considerations raised during the regulatory and ethics review of platform clinical trials in infectious diseases. [PDF]

Contemp Clin Trials Commun
de Jong AJ, van Hout D, Verberk JDM, Hensgens MPM, van der Velden AW, van de Wijgert JHHM, Bonten MJM, Derde LPG.   +7 more
europepmc   +1 more source

Guiding Ethics Review in Pharmacy Education Research and Scholarship at UBC: Clarifying the Unclear. [PDF]

Innov Pharm, 2021
Albon SP, Hu F.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Development of an evaluation indicator system for the quality of science and technology ethics review committees: a Chinese study based on the structure-process-outcome framework. [PDF]

BMC Med Ethics
Wu Y, Yang L, Liu X, Zhang X, Guénier AW, Wang X.   +5 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Ethics review or compliance check? an empirical analysis of 6740 requests for information in Belgian clinical trial evaluations (2017-2024). [PDF]

BMC Med Ethics
Van Scharen A, Deneyer M, Cornu P.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Strengthening ethics review of the development of artificial intelligence (AI) systems in health research: a guide for research ethics committees in Uganda. [PDF]

BMC Med Ethics
Nabukenya S, Wasswa W, Twimukye A, Mwaka ES.   +3 more
europepmc   +1 more source