Results 171 to 180 of about 2,047,734 (258)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Ethical Approval Waiver in the Shivamogga KFD Outbreak Investigation: Concerns and Call for Expedited Ethics Review Framework. [PDF]

Int J Public Health
Kumar S P.
europepmc   +1 more source

Research ethics review during the COVID-19 pandemic: An international study

, 2023
Salamanca-Buentello F, Katz R, Silva DS, Upshur RE, Smith MJ.   +4 more
europepmc   +1 more source

Composition and capacity of Institutional Review Boards, and challenges experienced by members in ethics review processes in Addis Ababa, Ethiopia: An exploratory qualitative study. [PDF]

Dev World Bioeth, 2023
Seralegne YZ, Wangamati CK, Wangamati CK, Bernabe RDLC, Farsides B, Aseffa A, Zewdie M.   +6 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Erratum: Requirements and special considerations for drug trials with children across six jurisdictions: 2. Ethics review in the regulatory approval process. [PDF]

Front Med (Lausanne)
Frontiers Production Office.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Relationships Between Ethical Conduct, Ethics Review and Education Within Scholarship of Teaching and Learning Research: Exploring Student Perspectives from Sweden and Aotearoa New Zealand. [PDF]

J Empir Res Hum Res Ethics
Lees AB, Godbold R, Walters S, Eliasson I.   +3 more
europepmc   +1 more source

"It's Almost as if Stakeholder Engagement is the Annoying 'Have-to-do'…": Can Ethics Review Help Address the "3 Ts" of Tokenism, Toxicity, and Tailoring in Stakeholder Engagement? [PDF]

J Empir Res Hum Res Ethics, 2022
Wilkinson A, Slack C, Thabethe S, Salzwedel J.   +3 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source