Results 181 to 190 of about 2,047,734 (258)

Ethical Design of Data-Driven Decision Support Tools for Improving Cancer Care: Embedded Ethics Review of the 4D PICTURE Project. [PDF]

JMIR Cancer
Bak M, Hartman L, Graafland C, Korfage IJ, Buyx A, Schermer M, 4D PICTURE Consortium.   +6 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Ethics Review of Biomedical Research in Uzbekistan: Policy and Program Gaps. [PDF]

Asian Bioeth Rev
Aniyozova D, Strosberg MA.
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Requirements and special considerations for drug trials with children across six jurisdictions: 2. Ethics review in the regulatory approval process. [PDF]

Front Med (Lausanne)
Stewart B, Lepola P, Egger GF, Ali F, Allen AJ, Croker AK, Davidson AJ, Dicks P, Faust SN, Green D, Hovinga C, Klein AV, Langham R, Nakamura H, Pioppo L, Ramroop S, Sakiyama M, Sanchez Vigil de la Villa I, Sato J, Snyder DL, Turner MA, Zaidi S, Zimmerman K, Lacaze-Masmonteil T.   +23 more
europepmc   +1 more source

A scoping review of the landscape of ethics review processes during public health emergencies in sub-Saharan Africa

, 2023
Orievulu K, Hinga A, Nkosi B, Ngwenya N, Seeley J, Gerald A, Tindana P, Molyneux S, Kinyanjui S, Kamuya D.   +9 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Ethics of editorial and peer review

Tropical Parasitology, 2012
Mandal, Jharna, Giri, Sidhartha, Parija, Subhash Chandra   +2 more
openaire   +3 more sources

Research ethics review during the COVID-19 pandemic: An international study. [PDF]

PLoS One
Salamanca-Buentello F, Katz R, Silva DS, Silva DS, Upshur REG, Smith MJ.   +5 more
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source