Results 31 to 40 of about 240,113 (263)

Energetics and Mechanism of Drug Transport Mediated by the Lactococcal Multidrug Transporter LmrP [PDF]

, 1996
The gene encoding the secondary multidrug transporter LmrP of Lactococcus lactis was heterologously expressed in Escherichia coli. The energetics and mechanism of drug extrusion mediated by LmrP were studied in membrane vesicles of E. coli. LmrP-mediated
Bolhuis, Henk,, Brands, Jan Roel,, Driessen, Arnold J.M.,, Konings, Wil N.,, Poolman, Bert,, Putman, Monique,, Veen, Hendrik W. van,   +6 more
core   +1 more source

Effects of Deletion of the Connexin 32 gene on pro and Anti-inflammatories Aspects in the Ethidium Bromide Toxic Demyelination Model

Brazilian Journal of Veterinary Pathology, 2012
Gap junctions are cellular structures that allow transit of molecules between cells, allowing intercellular signaling and transportation. They are formed by proteins denominated connexins and represent key structures in highly complex and integrated ...
Fernando Y. M. Hosomi, Luciano Fernandes Sousa, Adriano T. Ramos, Paulo C. Maiorka   +3 more
doaj   +1 more source

Application of Pulsed Field Gel Electrophoresis to Determine γ-ray-induced Double-strand Breaks in Yeast Chromosomal Molecules [PDF]

, 1993
The frequency of DNA double-strand breaks (dsb) was determined in yeast cells exposed to γ-rays under anoxic conditions. Genomic DNA of treated cells was separated by pulsed field gel electrophoresis, and two different approaches for the evaluation of ...
A.A. Friedl, A.M. Kellerer, Ager D.D., Ager D.D., Ahn S.Y., Andrews J., Blazek E.R., Blöcher D, Blöcher D, Blöcher D., Blöcher D., Blöcher D., Bronstein I., Contopoulou C.R., F. Eckardt-Schupp, Frankenberg D., Frankenberg-Schwager M., Geigl E.-M., Geigl E.-M., Geigl E.-M., Geigl E.-M., Hanawalt P.C, Ho K.S.Y, Iliakis G.E., Iliakis G.E., Jacobs A., K. Hahn, Kessler B., Kunz B.A., Lennartz M., Okayasu R.B., Oleinick N.L., Radford I.R., Resnick M.A., Schulz G.V, Smith L.C., Stamato T.D., Terleth C., W. Beisker, Ward J.F   +39 more
core   +1 more source

Ethidium Bromide Inhibits Mitochondrial Phosphorylating Oxidation

Experimental Biology and Medicine, 1975
Ethidium bromide, in addition to combination with mitochondrial nucleic acids, is a phosphorylation inhibitor during glutamate and succinate respiration by mitochondria. Exhaustive washing of ethidium bromide-treated mitochondria did not relieve the inhibition nor significantly decrease the amount of bound dye.
E S, Higgins, B L, Dunlavey, W H, Friend, K S, Rogers   +3 more
openaire   +2 more sources

Hypoxia-induced mitochondrial stress granules

Cell Death and Disease, 2023
Perturbations of mitochondrial proteostasis have been associated with aging, neurodegenerative diseases, and recently with hypoxic injury. While examining hypoxia-induced mitochondrial protein aggregation in C.
Chun-Ling Sun, Marc Van Gilst, C. Michael Crowder   +2 more
doaj   +1 more source

Highly Sensitive Detection of DNA Fragments by an Inexpensive and Simple Method Fabricated In-House Blue LED Transilluminator

Genetics & Applications, 2023
Agarose gel electrophoresis is a routinely employed experimental technique for visualizing nucleic acids, typically combined with ethidium bromide or some other molecular dye staining and a UV transilluminator.
Ryosuke Ishii
doaj   +1 more source

Transition on the entropic elasticity of DNA induced by intercalating molecules

, 2007
We use optical tweezers to perform stretching experiments on DNA molecules when interacting with the drugs daunomycin and ethidium bromide, which intercalate the DNA molecule.
Ferreira, M. C., Mesquita, O. N., Rocha, M. S.   +2 more
core   +1 more source

DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores [PDF]

, 1990
Dynemicin is a hybrid containing anthraquinone and enediyne cores, which contribute to binding and cleavage of DNA, respectively. DNA strand scission by the antitumor antibiotic is significantly enhanced by the addition of NADPH or thiol compounds.
Konishi, Masataka, Oki, Toshikazu, Shiraki, Takashi, Sugiura, Yukio   +3 more
core   +1 more source

HLA-G: expression in human keratinocytes in vitro and in human skin in vivo [PDF]

, 1994
Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity.
Ulbrecht, M., Rehberger, B., Strobel, I., Messer, Gerald, Kind, P., Degitz, K., Bieber, T., Weiss, Elisabeth H.   +7 more
core   +2 more sources

Chromosomal Abnormalities resulting from Ethidium Bromide Treatment

Nature, 1969
THE phenanthridine compound ethidium bromide (EB) has been extensively used as a trypanocidal agent. Its pharmacological effectiveness must be partially based on its intercalation with DNA molecules1,2, which alters the structure and hence the physical properties of the nucleic acid and which has recently facilitated the separation of molecules of ...
Vacquier, V D, Brachet, Jean
openaire   +3 more sources