Results 111 to 120 of about 282,497 (309)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Geoadria, 2015 This paper contains the analysis of maps and textual geographical descriptions (pilot) of the Zadar maritime zone from the work Kitâb-ı Bahriye (Book of Navigation) by Pîrî Reis, an Ottoman seafarer, pirate and later admiral.
Mithad Kozličić +2 more
doaj +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
To the Issue of Studying Ethnic Markers of Kalmyks: Clan Tamghas
Oriental Studies, 2018 The article considers Kalmyk tamghas in terms of studying ethnic markers and clan structure of Kalmyks as well as transformation processes in management forms.
T. Sharaeva
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Ethnic patriotism and markets in African history
, 2012 African economic and social history since 1800 suggests that the relationships between ethnic consciousness and market transaction is very varied and largely unpredictable. The early twentieth century was a period of important change. Before 1900 labour was scarce and land abundant: inter-ethnic relations were relatively flexible, thanks to a general ...
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Indians and Immigrants- Entangled Histories
, 2014 The article explores the history of inter-ethnic relations between Indians and Scandinavian immigrants in the U.S. Midwest. The author reflects on processes of migration, ethnicity and colonialism during Swedish, Norwegian, and Finnish immigration in the
Fur, Gunlög,, Gunlög Fur
core +1 more source
Oriental Studies, 2018 This article deals with the problems of the origin of Tsokhurovski ulus of the Kalmyk khanate, its history in the 18th century, as well as the problems of the formation of ethnic groups in a nomadic state.
Valery Batyrov
doaj