Results 121 to 130 of about 282,497 (309)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Problems with the census conception of ethnic group: an anthropological perspective

open access: yes, 2004
From the perspective of social anthropology, this paper examines the collection and analysis of census data on ethnic group membership. It identifies a fundamental problem lying in the census's attempt to enumerate a subjective identity.
Barber, Keith
core  

The Scientific School of A.S. Skripkin

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2015
The article is devoted to the creation of the scientific archaeological school of A.S. Skripkin that was taking place during the establishment of the Volgograd State University and the formation of its scientific and educational structures. A.S. Skripkin’
Dyachenko Aleksandr Nikolaevich
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Experience, Memory and Narrative: A Biographical Analysis of Ethnic Identity [PDF]

open access: yes
In the first part of this paper, we will introduce the theoretical framework for analyzing autobiographical narratives as it has been developed by the German sociologists Fritz Schütze and Gabriele Rosenthal3, and later has been adapted by Koleva, Popova
Teodora Karamelska, Christian Geiselmann
core  

Diversifying the uniform? The participation of minority ethnic personnel in the British armed services

open access: yes, 2003
This paper considers the pressures on the British armed services to increase the participation of minority ethnic groups and assesses recent government policy on this issue.
Mason, D, Dandeker, C
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

"A Demographic Base for Ethnic Survival? Blending Across Four Generations of German-Americans" [PDF]

open access: yes
New data from the IPUMS (Integrated Public Use Microdata Series) project permit an exploration of the demographic basis for ethnic survival across successive generations.
Joel Perlmann
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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