Results 121 to 130 of about 8,556,350 (292)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 7 No. 1

open access: yes, 1986
Seven page newsletter from the Ethnic Studies department dated Fall 1986. Newsletter is Volume 7, Number 1. Newsletter includes Feature on Joan Guillory; Faculty Accomplishments; News Items consisting primarily of events and organizations; and list of ...
Ethnic Studies Department;
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Ph. D. of History, Head of Ethnology sector of the Kalmyk Institute for Humanities Studies of the Russian Academy of Sciences

open access: yesOriental Studies, 2018
This article deals with the problems of the origin of Tsokhurovski ulus of the Kalmyk khanate, its history in the 18th century, as well as the problems of the formation of ethnic groups in a nomadic state.
Valery Batyrov
doaj  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

The Scientific School of A.S. Skripkin

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2015
The article is devoted to the creation of the scientific archaeological school of A.S. Skripkin that was taking place during the establishment of the Volgograd State University and the formation of its scientific and educational structures. A.S. Skripkin’
Dyachenko Aleksandr Nikolaevich
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 4 No. 4

open access: yes, 1984
Eight page newsletter from the Ethnic Studies department dated Spring 1984. Newsletter is Volume 4, Number 4. Newsletter includes pieces on Asian Pacific Heritage Week and a list of events; The Important of Cinco de Mayo; Heritage Week Events 1984; Paulo
Ethnic Studies Department;
core   +1 more source

Oral History and Ethnic History

open access: yes
https://cha-shc.ca/wp-content/uploads/2022/08/5c374f7f40a56 ...
openaire  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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