Results 121 to 130 of about 282,497 (309)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Problems with the census conception of ethnic group: an anthropological perspective
From the perspective of social anthropology, this paper examines the collection and analysis of census data on ethnic group membership. It identifies a fundamental problem lying in the census's attempt to enumerate a subjective identity.
Barber, Keith
core
The Scientific School of A.S. Skripkin
The article is devoted to the creation of the scientific archaeological school of A.S. Skripkin that was taking place during the establishment of the Volgograd State University and the formation of its scientific and educational structures. A.S. Skripkin’
Dyachenko Aleksandr Nikolaevich
doaj
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Experience, Memory and Narrative: A Biographical Analysis of Ethnic Identity [PDF]
In the first part of this paper, we will introduce the theoretical framework for analyzing autobiographical narratives as it has been developed by the German sociologists Fritz Schütze and Gabriele Rosenthal3, and later has been adapted by Koleva, Popova
Teodora Karamelska, Christian Geiselmann
core
This paper considers the pressures on the British armed services to increase the participation of minority ethnic groups and assesses recent government policy on this issue.
Mason, D, Dandeker, C
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
"A Demographic Base for Ethnic Survival? Blending Across Four Generations of German-Americans" [PDF]
New data from the IPUMS (Integrated Public Use Microdata Series) project permit an exploration of the demographic basis for ethnic survival across successive generations.
Joel Perlmann
core
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

