Results 131 to 140 of about 6,375,128 (341)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Scientific School of A.S. Skripkin

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2015
The article is devoted to the creation of the scientific archaeological school of A.S. Skripkin that was taking place during the establishment of the Volgograd State University and the formation of its scientific and educational structures. A.S. Skripkin’
Dyachenko Aleksandr Nikolaevich
doaj  

Ethnosizing Immigrants [PDF]

open access: yes
The paper provides a new measure of the ethnic identity of immigrants and explores its evolution in the host country. The ethnosizer, a measure of the intensity of a person's ethnic identity, is constructed from information on the following elements ...
Amelie Constant   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Ethnic Studies in the Twenty-First Century: A Proposal [PDF]

open access: yes, 1988
If you will consider the dualistic thinking which undergirds Western philosophical tradition, then it comes as a surprise to no one that the periodization of history is based on white male experiences as the sum of western civilization, especially the ...
Irby, Charles C.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Zadarski akvatorij u Pîrî Reisovoj Knjizi pomorstva iz 1526. godine: Pomorsko-geografske slike dijela hrvatskoga Jadrana

open access: yesGeoadria, 2015
U radu su analizirane karte i tekstualni geografski opisi (peljar) zadarskog akvatorija iz djela Kitâb-ı Bahriye (Knjiga pomorstva) osmanskog moreplovca, pirata i kasnije admirala Pîrî Reisa.
Mithad Kozličić   +2 more
doaj  

A note on race, ethnicity and nativity differentials in remarriage in the United States [PDF]

open access: yes
The objectives of this study are to produce up-to-date estimates of race/ethnic/nativity differentials for remarriage and repartnership among women in the United States and to see if these differences are due to across-group differences in demographic ...
Catherine B. McNamee, R. Kelly Raley
core  

Female Power, Ethnicity, and Aging [PDF]

open access: yes, 1986
The standard academic presentation on the topic of power rarely alludes to the elderly, ethnic groups, or to females of any age or race. The cultural history of humankind has been one of gross inequities in the distribution of power, and much of this ...
Abbott, Linda M. C.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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