Results 41 to 50 of about 186,917 (199)

Flavonoid chemical composition and antidiabetic potential of Brachychiton acerifolius leaves extract

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To evaluate Brachychiton acerifolius leaf extracts as antidiabetic potential agent and to identify the main active constituents using bioactivity guided fractionation. Methods: In vitro antioxidant activity was evaluated for B.
Aisha Hussein Abou Zeid, Mohamed Ali Farag, Manal Abdel Aziz Hamed, Zeinab Abdel Aziz Kandil, Radwa Hassan El-Akad, Hanaa Mohamed El-Rafie   +5 more
doaj   +1 more source

Polyphenol composition and antioxidant activity of Searsia tripartita and Limoniastrum guyonianum growing in Southeastern Algeria

Scientific African, 2020
Due to the notable medicinal value of Searsia tripartita and Limoniastrum guyonianum, it was of great interest to conduct phytochemical and antioxidant investigations.
Soumia Hadjadj, Marie-Andrée Esnault, Solenne Berardocco, Sylvain Guyot, Alain Bouchereau, Fatima Ghouini, Razika Lamini, Aminata Ould El Hadj-Khelil   +7 more
doaj   +1 more source

Evaluation of a new immunoassay for urinary ethyl glucuronide testing [PDF]

Alcohol and Alcoholism, 2007
The minor ethanol metabolite ethyl glucuronide (EtG) is used as a sensitive and specific test for recent alcohol consumption with clinical and forensic applications. This study evaluated a new enzyme immunoassay (DRI-EtG EIA, Microgenics Corp.) for determination of the EtG concentration in urine samples.Evaluation was done using the kit calibrators ...
Michael, Böttcher, Olof, Beck, Anders, Helander   +2 more
openaire   +2 more sources

Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants. [PDF]

, 2012
BACKGROUND: Alcohol makes an important contribution to premature mortality in many countries in Eastern Europe, including Estonia. However, the full extent of its impact, and the mechanisms underlying it, are challenging issues to research.
Tõnisson, Mailis, McKee, Martin, Paerna, K, Helander, A,, Pärna, Kersti, Leon, DA, Lang, K, McKee Martin, Väli, Marika, Tuusov, J, Ringmets, I, Väli Marika, Tuusov Jana, Lang, Katrin, Vaeli, M, Tõnisson Mailis, Lang Katrin, Ringmets, Inge, Ringmets Inge, Helander Anders, Leon, David A, Helander, Anders, Pärna Kersti, Leon David A, McKee, M, Tonisson, M, Tuusov, Jana   +26 more
core   +1 more source

Ethyl Glucuronide and Ethyl Sulphate in Urine: Caution in their use as markers of recent alcohol use

, 2020
To clarify the role of the ethanol metabolites, ethyl glucuronide (EtG) and ethyl sulfate (EtS), in monitoring alcohol ...
Mercurio, Umberto, Bacci, Mauro, Lancia, Massimo, Troiano, Gianmarco, Pellegrino, Adriana, Gili, Alessio, Sannicandro, Domenico, Rettagliata, George, Melai, Paola, Agostinelli, Fausto, Mercurio, Isabella, Politi, Pamela, Mezzetti, Eleonora   +12 more
core   +1 more source

EtG Quantification in Hair and Different Reference Cut-Offs in Relation to Various Pathologies: A Scoping Review

Toxics, 2022
Ethyl glucuronide (EtG) is a non-volatile, non-oxidative, hydrophilic, and stable ethanol phase II metabolite. EtG is produced through ethanol glucuronidation by UDP-glucuronosyltransferase (UGT), a phase II enzyme.
Valentina Triolo, Mario Spanò, Roberto Buscemi, Simona Gioè, Ginevra Malta, Marija Čaplinskiene, Fabio Vaiano, Elisabetta Bertol, Stefania Zerbo, Giuseppe Davide Albano, Antonina Argo   +10 more
doaj   +1 more source

ANTI-INFLAMMATORY ACTIVITY OF THE FOOD PLANT CALLIGONUM POLYGONOIDES L. FLAVONOIDS TARGETING NF-κB [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2020
Calligonum polygonoides L. subsp. comosum (Polygonaceae) is a wild shrub that grows on the sandy deserts of various regions in North Africa, Western Asia and Southern Europe. In some of Asian countries, the flower buds and young branches of the plant are
Nesma Mohamed, Mai Ahmed, Ahmed Zaher
doaj   +1 more source

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Biomolecules and Biomarkers Used in Diagnosis of Alcohol Drinking and in Monitoring Therapeutic Interventions

Biomolecules, 2015
Background: The quantitative, measurable detection of drinking is important for the successful treatment of alcohol misuse in transplantation of patients with alcohol disorders, people living with human immunodeficiency virus that need to adhere to ...
Radu M. Nanau, Manuela G. Neuman
doaj   +1 more source

Hours Since Last Drink Is Associated With Multiple Urine Ethyl Glucuronide Cutoffs Among Individuals With Alcohol Use Disorder

Drug Testing and Analysis, EarlyView.
Higher uEtG results indicated more recent drinking, rather than higher levels of alcohol consumption, and the period of detection of uEtG was shorter than previously reported. Even at low cutoffs, uEtG was best conceptualized as a measure of alcohol consumption in the prior 24 h.
Julianne D. Jett, Mohammad Keshtkar, Emma Seidler, Katharine Palmer, Diana Tyutyunnyk, Rachael Beck, Sara C. Parent, Douglas L. Weeks, Naomi Chaytor, Sterling M. McPherson, Michael G. McDonell   +10 more
wiley   +1 more source