GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity [PDF]
Gap junctions within the cerebral cortex may facilitate cortical seizure formation by their ability to synchronize electrical activity. To investigate this, one option is to compare wild-type (WT) animals with those lacking the gene for connexin36 (Cx36 ...
Melin, Sofia M. +11 more
core +1 more source
Background: The very idea of faster recovery and early ambulation has prompted patients to opt for day care surgeries. The concept of ERAS (enhanced recovery after surgery) is the backbone to achieve this goal.
Jyoti Kale +3 more
doaj +1 more source
Effect of ciprofol-etomidate mixtures for deep sedation during gastrointestinal endoscopy: Protocol for a three-arm, double-blind randomized controlled trial. [PDF]
Xu B +9 more
europepmc +2 more sources
Feasibility and safety of etomidate based deep sedation protocol for pulsed field electroporation in atrial fibrillation ablation [PDF]
A Nekic +6 more
europepmc +2 more sources
Background and Aims: Studies comparing the effect of propofol and etomidate on hemodynamic parameters during electroconvulsive therapy (ECT) have shown ambiguous results.
Divya Mehta +3 more
doaj +1 more source
Novel etomidate derivatives [PDF]
Etomidate is a well established intravenous anaesthetic agent which has been widely used. Recognised limitations of the agent include adrenocortical suppression, myoclonus and post-operative nausea and vomiting, PONV.
Sneyd, J. Robert
core +1 more source
Minimum infusion rate and adrenocortical function after continuous infusion of the novel etomidate analog ET-26-HCl in rats [PDF]
Background Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate ...
Junli Jiang +5 more
doaj +2 more sources
Etomidate for critically ill patients. Con: do you really want to weaken the frail? [PDF]
Etomidate is an imidazole-derived hypnotic agent preferentially used for rapid sequence induction of anaesthesia because of its favourable haemodynamic profile.
Walder, Bernhard +2 more
core +1 more source
Anesthetic Consideration of Patient With Myotonic Dystrophy Type 1: A Case Report and Review of Literature. [PDF]
ABSTRACT Myotonic dystrophy type 1 (DM1) presents significant anesthetic challenges. A 46‐year‐old woman with DM1 underwent emergent exploratory laparotomy. This case highlights the importance of conservative neuromuscular blocker dosing, quantitative neuromuscular monitoring, clinically‐guided timing of sugammadex administration, careful airway ...
Lin YC +7 more
europepmc +2 more sources
Etomidate - a review of robust evidence for its use in various clinical scenarios [PDF]
Etomidate is an intravenous hypnotic with a favourable clinical profile in haemodynamic high-risk scenarios. Currently, there is an active debate about the clinical significance of the drug's side effects and its overall risk-benefit ratio.
Basciani, Reto Marco +2 more
core +1 more source

