Results 41 to 50 of about 20,342 (251)

Year in review in Intensive Care Medicine 2012. II: Pneumonia and infection, sepsis, coagulation, hemodynamics, cardiovascular and microcirculation, critical care organization, imaging, ethics and legal issues. [PDF]

, 2013
Journal ArticleSCOPUS: re.jSCOPUS: re.jinfo:eu-repo/semantics ...
Antonelli, Massimo, Bonten, Marc, Cecconi, Maurizio, Chastre, Jean, Citerio, Giuseppe, Conti, Giorgio, Curtis, J.Randall, Hedenstierna, Goran, Joannidis, Michael, Macrae, Duncan, Maggiore, Salvatore M., Mancebo, Jordi, Mebazaa, Alexandre, Preiser, Jean Charles, Rocco, Patricia, Timsit, Jean François, Universitat Autònoma de Barcelona, Wernerman, Jan, Zhang, H.   +18 more
core   +2 more sources

Etomidate and propylene glycol activate nociceptive TRP ion channels

Molecular Pain, 2018
Background Etomidate is a preferred drug for the induction of general anesthesia in cardiovascular risk patients. As with propofol and other perioperatively used anesthetics, the application of aqueous etomidate formulations causes an intensive burning ...
Florian Niedermirtl, Mirjam Eberhardt, Barbara Namer, Andreas Leffler, Carla Nau, Peter W Reeh, Katrin Kistner   +6 more
doaj   +1 more source

Propofol, Ketamine, and Etomidate as Induction Agents for Intubation and Outcomes in Critically Ill Patients: A Retrospective Cohort Study

Critical Care Explorations, 2021
Supplemental Digital Content is available in the text. IMPORTANCE: Propofol, ketamine, and etomidate are common anesthetic agents for induction of anesthesia in the ICU.
C. Wan, A. Hanson, P. Schulte, Yue Dong, P. Bauer   +4 more
semanticscholar   +1 more source

Etomidate derivatives: Novel pharmaceutical agents in anesthesia

Journal of Anaesthesiology Clinical Pharmacology, 2017
Etomidate is an imidazole derivative that possesses important sedative properties employed in anesthesia practice, however, etomidate has a number of well-know side effects which limit its use in certain subpopulations and over long periods of time ...
Raymond J Malapero, Michael P Zaccagnino, Ethan Y Brovman, Alan David Kaye, Richard D Urman   +4 more
doaj   +1 more source

Dexamethasone alleviates etomidate-induced myoclonus by reversing the inhibition of excitatory amino acid transporters

Frontiers in Neuroscience
BackgroundEtomidate can induce myoclonus with an incidence of 50 ~ 85% during anesthesia induction. Dexamethasone, as a long-acting synthetic glucocorticoid, has neuroprotective effects.
Yan Feng, Yan Feng, Min Zhang, Shuai-ying Jia, Yan-xia Guo, Xue Jia, Xue Jia   +6 more
doaj   +1 more source

Electroencephalographic dynamics of etomidate‐induced loss of consciousness

BMC Anesthesiology, 2021
Background Highly structured electroencephalography (EEG) oscillations can occur in adults during etomidate-induced general anesthesia, but the link between these two phenomena is poorly understood.
Lei Zhang, Shunqin Fan, Jiawei Zhang, Kun Fang, Lei Wang, Yuanyuan Cao, Lijian Chen, Xuesheng Liu, Erwei Gu   +8 more
doaj   +1 more source

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Ketamine versus etomidate as an induction agent for tracheal intubation in critically ill adults: a Bayesian meta-analysis

Critical Care
Tracheal intubation is a high-risk intervention commonly performed in critically ill patients. Due to its favorable cardiovascular profile, ketamine is considered less likely to compromise clinical outcomes.
Takatoshi Koroki, Yuki Kotani, Takahiko Yaguchi, Taisuke Shibata, Motoki Fujii, S. Fresilli, Mayuko Tonai, Toshiyuki Karumai, Todd C Lee, G. Landoni, Yoshiro Hayashi   +10 more
semanticscholar   +1 more source

Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway

Experimental and Therapeutic Medicine, 2021
The present study aimed to investigate the protective effects of etomidate on hyperoxia-induced acute lung injury in mice, particularly on the nuclear factor-erythroid 2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1) pathway.
Liming Jia, Hongzhong Hao, Chunyu Wang, Jian-feng Wei   +3 more
semanticscholar   +1 more source

Detection of Etomidate and Etomidate Acid in Urine Using HPLC-MS/MS Method

Fayixue Zazhi
ObjectiveTo establish a high performance liquid chromatography-tandem mass spectrometry （HPLC-MS/MS） method for the detection of etomidate and etomidate acid in urine samples.MethodsProtein in the urine samples was precipitated by adding acetonitrile ...
HE Tian-fu, ZHU Huan-hui, TIAN Yuan-yuan, JIN Yin-shuang, LIN Xian-wen, WANG Song-cai   +5 more
doaj   +1 more source