Results 21 to 30 of about 9,607 (202)

Effect of dexmedetomidine on etomidate-induced myoclonus: a randomized, double-blind controlled trial

Drug Design, Development and Therapy, 2019
Shuai Miao,1,2 Lan Zou,1,2 Guanglei Wang,1,2 Xiuli Wang,1,2 Su Liu,1,2 Mengzhu Shi1,21Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of Anesthesiology, The Affiliated ...
Miao S, Zou L, Wang G, Wang X, Liu S, Shi M   +5 more
doaj   +1 more source

Butorphanol pre-treatment prevents myoclonus induced by etomidate

Swiss Medical Weekly, 2014
QUESTIONS UNDER STUDY: Myoclonic movements are common problems during induction of anaesthesia with etomidate. The myoclonus occurring after etomidate administration may represent a form of seizure.
Liang He, Ying Ding, Huiyu Chen, Yanning Qian, Zhong Li   +4 more
doaj   +2 more sources

Effects of etomidate use in ICU patients on ventilator therapy: a study of 12,526 patients in an open database from a single center [PDF]

Korean Journal of Anesthesiology, 2021
Background There is a debate regarding the safety of etomidate. We evaluated the effects of etomidate on mortality in a large cohort of critical care patients.
Ha Yeon Park, Younsuk Lee, Chi-Yeon Lim, Mina Kim, Jieun Park, Teakseon Lee   +5 more
doaj   +1 more source

Polymorphisms of pharmacogenetic candidate genes affect etomidate anesthesia susceptibility

Frontiers in Genetics, 2022
Purpose: Etomidate is widely used in general anesthesia and sedation, and significant individual differences are observed during anesthesia induction.
Lulin Ma, Yan Huang, Yan Huang, Shiqian Huang, Feng Xu, Yafeng Wang, Shuai Zhao, Daling Deng, Yuanyuan Ding, Tianhao Zhang, Wenjing Zhao, Xiangdong Chen   +11 more
doaj   +1 more source

Effect of priming in preventing myoclonic movements after intravenous induction with etomidate in adult patients undergoing cardiac surgery: a randomised controlled interventional study

Journal of Applied Pharmaceutical Research, 2022
Etomidate is a hypnotic drug used as an intravenous anaesthetic induction agent. Etomidate causes myoclonic movements in 50-80% patients after induction which makes it less desirable for induction.
Mukesh K Sunda, Kanchan Chauhan, Rajeev Kumar Prajapati, Krishna Boliwal   +3 more
doaj   +1 more source

Comparison of Pain on Injection of Etomidate versus Etomidate-Lipuro in Patients Undergoing Elective Orthopedic Surgery: A Double-Blind Randomized Clinical Trial

Journal of Orthopedic and Spine Trauma, 2021
Background: Etomidate is an efficient general anesthetic associated with injection pain. Etomidate-Lipuro is its lipid emulsion, suggested to have less adverse effects. We aim to compare the injection pain of etomidate vs.
Alireza Saliminia, Niloofar Esfahanian
doaj   +1 more source

Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BMC Pharmacology and Toxicology, 2019
Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects.
Megan McGrath, Alissa Hofmann, Douglas E. Raines   +2 more
doaj   +1 more source

Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]

, 1988
We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Winkelmann, W., Schulte, H. M., Allolio, B., Kaulen, D., Jaursch-Hancke, C., Reincke, Martin   +5 more
core   +1 more source

Assessment of Psychomotor Recovery after Etomidate and Propofol Induction: A Randomized Double-Blind Trial

Archives of Anesthesia and Critical Care, 2021
Background: The very idea of faster recovery and early ambulation has prompted patients to opt for day care surgeries. The concept of ERAS (enhanced recovery after surgery) is the backbone to achieve this goal.
Jyoti Kale, Neha Panse, Ketki Maske, Pranali Nighukar   +3 more
doaj   +1 more source

Effect of vitamin C on adrenal suppression following etomidate for rapid sequence induction in trauma patients: a randomized clinical trial

BMC Anesthesiology, 2023
Background Etomidate is an imidazole derivative that is widely used in the emergency department for Rapid Sequence Intubation (RSI). Although it has a safe hemodynamic profile, there are some concerns about its suppressant effects on the adreno-cortical ...
Jafar Rahimi Panahi, Seyed Pouya Paknezhad, Amir vahedi, Kavous Shahsavarinia, Manuchehr Ruhi Laleh, Hassan Soleimanpour   +5 more
doaj   +1 more source