Results 21 to 30 of about 20,342 (251)
Brazilian Journal of Anesthesiology, 2022 Background: Though hemodynamically stable, etomidate is known for its myoclonus side effect following induction. The main aim of this study is an effective attempt to decrease the incidence of myoclonus with a priming agent.
Srilata Moningi +5 more
doaj +1 more source
Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]
, 1988 We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Allolio, B. +5 more
core +1 more source
JAMA Surgery, 2022 This randomized clinical trial compares the in-hospital morbidity, clinical outcomes, and mortality associated with use of etomidate vs propofol during abdominal surgery in older patients in China.
Zhihong Lu +48 more
semanticscholar +1 more source
Drug Design, Development and Therapy, 2021 Objective The optimal sedation regime during endoscopy remains controversial, especially for elderly outpatients. In this study, we compared the efficacy and safety between remimazolam tosilate (RT) and etomidate-propofol (EP) in elderly outpatients ...
Xian-wen Liu +6 more
semanticscholar +1 more source
GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity [PDF]
, 2010 Gap junctions within the cerebral cortex may facilitate cortical seizure formation by their ability to synchronize electrical activity. To investigate this, one option is to compare wild-type (WT) animals with those lacking the gene for connexin36 (Cx36 ...
Jacobson, Gregory M. +3 more
core +2 more sources
BMC Anesthesiology, 2023 Background Etomidate is an imidazole derivative that is widely used in the emergency department for Rapid Sequence Intubation (RSI). Although it has a safe hemodynamic profile, there are some concerns about its suppressant effects on the adreno-cortical ...
Jafar Rahimi Panahi +5 more
doaj +1 more source
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
, 2018 BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E. +12 more
core +1 more source
American Journal of Emergency Medicine, 2022 INTRODUCTION Emergency department (ED) patients undergoing emergent tracheal intubation often have multiple physiologic derangements putting them at risk for post-intubation hypotension.
M. Foster +6 more
semanticscholar +1 more source
Libyan Journal of Medicine, 2023 Etomidate is an anesthetic agent used in hemodynamically unstable patients, but its use has been controversial in septic patients. The response of high-mobility group box 1 (HMGB1), a late-phase lethal cytokine in sepsis, to etomidate has not been ...
Yoo Jung Park +6 more
doaj +1 more source
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition [PDF]
, 2014 Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a
Alkire +57 more
core +3 more sources