UPLC-MS/MS Method for Detection of Etomidate and Its Metabolite Etomidate Acid Quantity in Blood [PDF]
Fayixue Zazhi, 2023 Objective To establish a method for the simultaneous quantitative analysis of etomidate and its metabolite etomidate acid in blood, and to discuss its application value in actual cases.
Xing HAN, Xin LIU, Ming-luo DU, Ruo-lun XU, Jia-rong LI, Chao LIU, Wei-guo LIU
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Etomidate derivatives: Novel pharmaceutical agents in anesthesia
Journal of Anaesthesiology Clinical Pharmacology, 2017 Etomidate is an imidazole derivative that possesses important sedative properties employed in anesthesia practice, however, etomidate has a number of well-know side effects which limit its use in certain subpopulations and over long periods of time ...
Raymond J Malapero +4 more
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Etomidate and propylene glycol activate nociceptive TRP ion channels [PDF]
Molecular Pain, 2018 Background Etomidate is a preferred drug for the induction of general anesthesia in cardiovascular risk patients. As with propofol and other perioperatively used anesthetics, the application of aqueous etomidate formulations causes an intensive burning ...
Florian Niedermirtl +6 more
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Effect of dexmedetomidine in preventing etomidate-induced myoclonus: a meta-analysis
Drug Design, Development and Therapy, 2017 Xueke Du,1 Chengmao Zhou,2 Linghui Pan,1 Changlong Li1 1Department of Anesthesiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 2Department of Surgery, Zhaoqing Medical College, Zhaoqing Shi, Guangdong Sheng, People’s ...
Du X, Zhou C, Pan L, Li C
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The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro. [PDF]
PLoS ONE, 2018 (R)-2-methoxyethyl1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride (ET-26 HCl) is a novel etomidate analogue. The purpose of this study was to characterize whether ET-26 HCl could retain the superior myocardial performance of etomidate in vivo ...
Xingxing Liu +7 more
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Case report: Side effects of etomidate in propylene glycol in five Göttingen Minipigs [PDF]
Frontiers in Veterinary ScienceEtomidate, an agonist of the GABA A receptors, is available for clinical use either in combination with 35% propylene glycol or in a lipid emulsion. Its recognized ability to minimally impact the cardiovascular system made etomidate a suitable option for
Mariafrancesca Petrucci +4 more
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Drug Design, Development and Therapy, 2019 Shuai Miao,1,2 Lan Zou,1,2 Guanglei Wang,1,2 Xiuli Wang,1,2 Su Liu,1,2 Mengzhu Shi1,21Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Department of Anesthesiology, The Affiliated ...
Miao S +5 more
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NH600001, an etomidate analogue, provides gastrointestinal endoscopy sedation/anesthesia and reduces adrenocortical depression: two randomized controlled trials [PDF]
Nature CommunicationsTo evaluate the efficacy and safety of NH600001, a novel etomidate derivative, in gastrointestinal endoscopy, as well as its impact on adrenocortical function, two multicenter, double-blind, randomized, controlled clinical trials(NH600001-21 [Phase II ...
Yingyong Zhou +37 more
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Comparative sedative effects of intravenous etomidate/fentanyl/midazolam versus propofol/fentanyl/midazolam combination for dental treatment of uncooperative children: a randomized clinical trial. [PDF]
Sci RepMozafar S +5 more
europepmc +3 more sources
Etomidate Is Associated with Higher 30-Day Mortality than Ketamine for Emergency Intubation of COVID-19 Patients: A Propensity-Matched Cohort Study. [PDF]
J Clin MedLin LW, Huang TF, Huang CC, Chong CF.
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