Results 11 to 20 of about 20,342 (251)

Anesthetic Strategies for Closed Reduction of Dislocated Total Hip Arthroplasty: A Scoping Review. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Background Total hip arthroplasty (THA) is a frequently performed orthopedic procedure, with dislocation being a common complication, often requiring closed reduction. Anesthetic strategies for this vary, and evidence on the efficacy, safety, and cost‐effectiveness of current strategies is limited.
Knudsen RL, Bjulf RHF, Bahuet AR, Steensbæk MT, Jellestad AL, Lange KHW, Lundstrøm LH, Nørskov AK.   +7 more
europepmc   +2 more sources

Effect of priming in preventing myoclonic movements after intravenous induction with etomidate in adult patients undergoing cardiac surgery: a randomised controlled interventional study

Journal of Applied Pharmaceutical Research, 2022
Etomidate is a hypnotic drug used as an intravenous anaesthetic induction agent. Etomidate causes myoclonic movements in 50-80% patients after induction which makes it less desirable for induction.
Mukesh K Sunda, Kanchan Chauhan, Rajeev Kumar Prajapati, Krishna Boliwal   +3 more
doaj   +1 more source

Comparison of Remimazolam Tosilate and Etomidate on Hemodynamics in Cardiac Surgery: A Randomised Controlled Trial

Drug Design, Development and Therapy, 2023
Background Remimazolam tosilate (RT) is a new ultrashort-acting γ-aminobutyric acid subtype A (GABAA) agonist, with the characteristics of rapid onset and offset, minimal cardiorespiratory depression. Currently, few studies have compared the effect of RT
Bailong Hu, Mei Zhang, Zhanghua Wu, Xiaoyuan Zhang, X. Zou, Li Tan, Tao Song, Xingyu Li   +7 more
semanticscholar   +1 more source

Comparison of Pain on Injection of Etomidate versus Etomidate-Lipuro in Patients Undergoing Elective Orthopedic Surgery: A Double-Blind Randomized Clinical Trial

Journal of Orthopedic and Spine Trauma, 2021
Background: Etomidate is an efficient general anesthetic associated with injection pain. Etomidate-Lipuro is its lipid emulsion, suggested to have less adverse effects. We aim to compare the injection pain of etomidate vs.
Alireza Saliminia, Niloofar Esfahanian
doaj   +1 more source

Clinical outcomes after a single induction dose of etomidate versus ketamine for emergency department sepsis intubation: a randomized controlled trial

Scientific Reports, 2023
Patients with sepsis often require emergency intubation. In emergency departments (EDs), rapid-sequence intubation with a single-dose induction agent is standard practice, but the best choice of induction agent in sepsis remains controversial.
Winchana Srivilaithon, Atidtaya Bumrungphanithaworn, Kiattichai Daorattanachai, Chitlada Limjindaporn, Kumpol Amnuaypattanapon, Intanon Imsuwan, Nipon Diskumpon, Ittabud Dasanadeba, Yaowapha Siripakarn, Thosapol Ueamsaranworakul, Chatchanan Pornpanit, Vanussarin Pornpachara   +11 more
semanticscholar   +1 more source

Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells. [PDF]

PLoS ONE, 2015
Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals.
Hua-Cheng Liu, Danyan Zhu, Chan Wang, Hongguo Guan, Senlin Li, Cong Hu, Zhichuan Chen, Yuanyuan Hu, Han Lin, Qing-Quan Lian, Ren-Shan Ge   +10 more
doaj   +1 more source

Assessment of Psychomotor Recovery after Etomidate and Propofol Induction: A Randomized Double-Blind Trial

Archives of Anesthesia and Critical Care, 2021
Background: The very idea of faster recovery and early ambulation has prompted patients to opt for day care surgeries. The concept of ERAS (enhanced recovery after surgery) is the backbone to achieve this goal.
Jyoti Kale, Neha Panse, Ketki Maske, Pranali Nighukar   +3 more
doaj   +1 more source

Realising the therapeutic potential of neuroactive steroid modulators of the GABA_A receptor [PDF]

, 2020
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia, Gee, Kelvin W., Hogenkamp, Derk, Lambert, Jeremy J.   +3 more
core   +1 more source

Etomidate and its Analogs: A Review of Pharmacokinetics and Pharmacodynamics

Clinical Pharmacokinetics, 2021
Etomidate is a hypnotic agent that is used for the induction of anesthesia. It produces its effect by acting as a positive allosteric modulator on the γ-aminobutyric acid type A receptor and thus enhancing the effect of the inhibitory neurotransmitter γ ...
Beatrijs I. Valk, M. Struys
semanticscholar   +1 more source

Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BMC Pharmacology and Toxicology, 2019
Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects.
Megan McGrath, Alissa Hofmann, Douglas E. Raines   +2 more
doaj   +1 more source