Results 11 to 20 of about 9,607 (202)

UPLC-MS/MS Method for Detection of Etomidate and Its Metabolite Etomidate Acid Quantity in Blood [PDF]

Fayixue Zazhi, 2023
Objective To establish a method for the simultaneous quantitative analysis of etomidate and its metabolite etomidate acid in blood, and to discuss its application value in actual cases.
Xing HAN, Xin LIU, Ming-luo DU, Ruo-lun XU, Jia-rong LI, Chao LIU, Wei-guo LIU
doaj   +2 more sources

Comparison of left ventricular diastolic function parameters in patients induced with propofol and etomidate: A randomized clinical trial [PDF]

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Anesthetic agents like propofol and etomidate are known to affect intracellular calcium homeostasis during diastole. Hence, this study has been designed to study the effects of etomidate and propofol on left ventricular diastolic ...
Shanmugappriya Arunachalam, Muthapillai Senthilnathan, Satyen Parida, Srinivasan Suganya, Mekala Ranjith Kumar, Sandeep Kumar Mishra   +5 more
doaj   +2 more sources

Etomidate derivatives: Novel pharmaceutical agents in anesthesia

Journal of Anaesthesiology Clinical Pharmacology, 2017
Etomidate is an imidazole derivative that possesses important sedative properties employed in anesthesia practice, however, etomidate has a number of well-know side effects which limit its use in certain subpopulations and over long periods of time ...
Raymond J Malapero, Michael P Zaccagnino, Ethan Y Brovman, Alan David Kaye, Richard D Urman   +4 more
doaj   +2 more sources

Isobolographic Analysis of the Interaction Between Remimazolam and Etomidate in General Anesthesia Induction: A Prospective, Sequential Allocation Study Based on the Dixon Up-and-Down Method [PDF]

Drug Design, Development and Therapy
Wei Yue,1,* Jiayan Huang,2,* Qi Wang,2 Furong Zheng,2 Pengfei Yin,3 Yaohua Jin,2 Yue Wang,4 Linzhong Zhang1 1College of Anesthesiology, Shanxi Medical University and Department of Anesthesiology, Second Hospital of Shanxi Medical ...
Yue W, Huang J, Wang Q, Zheng F, Yin P, Jin Y, Wang Y, Zhang L   +7 more
doaj   +2 more sources

Etomidate and propylene glycol activate nociceptive TRP ion channels

Molecular Pain, 2018
Background Etomidate is a preferred drug for the induction of general anesthesia in cardiovascular risk patients. As with propofol and other perioperatively used anesthetics, the application of aqueous etomidate formulations causes an intensive burning ...
Florian Niedermirtl, Mirjam Eberhardt, Barbara Namer, Andreas Leffler, Carla Nau, Peter W Reeh, Katrin Kistner   +6 more
doaj   +2 more sources

Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells. [PDF]

PLoS ONE, 2015
Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals.
Hua-Cheng Liu, Danyan Zhu, Chan Wang, Hongguo Guan, Senlin Li, Cong Hu, Zhichuan Chen, Yuanyuan Hu, Han Lin, Qing-Quan Lian, Ren-Shan Ge   +10 more
doaj   +2 more sources

Effect of ciprofol with etomidate on the occurrence of hypotension in elderly patients undergoing upper gastrointestinal endoscopy: a prospective randomized controlled study [PDF]

BMC Anesthesiology
Background Ciprofol is increasingly used for endoscopic sedation due to its reduced injection pain, but evidence regarding its safety when combined with etomidate in elderly patients remains limited.
Zeyu Guo, Yuan Xiao, Xinru Li, You Wang, Yi Yang, Chengxi Liu, Wenjie Liu   +6 more
doaj   +2 more sources

Effect of dexmedetomidine in preventing etomidate-induced myoclonus: a meta-analysis

Drug Design, Development and Therapy, 2017
Xueke Du,1 Chengmao Zhou,2 Linghui Pan,1 Changlong Li1 1Department of Anesthesiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 2Department of Surgery, Zhaoqing Medical College, Zhaoqing Shi, Guangdong Sheng, People’s ...
Du X, Zhou C, Pan L, Li C
doaj   +1 more source

Comparing the Impact of Metoclopramide versus Ondansetron on Pain Reduction Caused by Etomidate Injection in Patients under General Anesthesia [PDF]

Advanced Biomedical Research
Background: Etomidate is a short-acting intravenous anesthetic commonly used for induction of general anesthesia and sedation. Preventing pain caused by etomidate injection can improve patient comfort and broaden its clinical use. This study compared the
Zahra Rahimi, Behzad Nazemroaya, Mehrdad Masoudifar, Nazanin Nazari   +3 more
doaj   +2 more sources

Case report: Side effects of etomidate in propylene glycol in five Göttingen Minipigs [PDF]

Frontiers in Veterinary Science
Etomidate, an agonist of the GABA A receptors, is available for clinical use either in combination with 35% propylene glycol or in a lipid emulsion. Its recognized ability to minimally impact the cardiovascular system made etomidate a suitable option for
Mariafrancesca Petrucci, Mariafrancesca Petrucci, Mariafrancesca Petrucci, Simone de Brot, Daniela Casoni   +4 more
doaj   +2 more sources