Results 31 to 40 of about 13,978 (200)
Effects of Etomidate on the Steroidogenesis of Rat Immature Leydig Cells. [PDF]
PLoS ONE, 2015 Etomidate is a rapid hypnotic intravenous anesthetic agent. The major side effect of etomidate is the reduced plasma concentration of corticosteroids, leading to the abnormal reaction of adrenals.
Hua-Cheng Liu +10 more
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Journal of Orthopedic and Spine Trauma, 2021 Background: Etomidate is an efficient general anesthetic associated with injection pain. Etomidate-Lipuro is its lipid emulsion, suggested to have less adverse effects. We aim to compare the injection pain of etomidate vs.
Alireza Saliminia, Niloofar Esfahanian
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Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats
BMC Pharmacology and Toxicology, 2019 Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects.
Megan McGrath +2 more
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Brazilian Journal of Anesthesiology, 2022 Background: Though hemodynamically stable, etomidate is known for its myoclonus side effect following induction. The main aim of this study is an effective attempt to decrease the incidence of myoclonus with a priming agent.
Srilata Moningi +5 more
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Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]
, 1988 We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Winkelmann, W. +5 more
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BMC Anesthesiology, 2023 Background Etomidate is an imidazole derivative that is widely used in the emergency department for Rapid Sequence Intubation (RSI). Although it has a safe hemodynamic profile, there are some concerns about its suppressant effects on the adreno-cortical ...
Jafar Rahimi Panahi +5 more
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Libyan Journal of Medicine, 2023 Etomidate is an anesthetic agent used in hemodynamically unstable patients, but its use has been controversial in septic patients. The response of high-mobility group box 1 (HMGB1), a late-phase lethal cytokine in sepsis, to etomidate has not been ...
Yoo Jung Park +6 more
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Histamine release after injection of benzodiazepines and of etomidate. A problem associated with the solvent propylene glycol (= Libération d'histamine après injection de benzodiazépines et d'étomidate. Rôle du solvant propylène-glycol) [PDF]
, 1993 Many drugs, especially when given in rapid sequence can cause histamine release. Ten healthy volunteers were premedicated with diazepam 10 mg.70 kg-1 i.v. and lormetazepam 1 mg.70 kg-1 i.v., respectively, 30 min prior to etomidate 0.15 mg.kg-1 i.v.
Doenicke, A. +4 more
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Outstanding Seizure Characteristics With Etomidate and Ketofol
European Psychiatry, 2022 Introduction Electroconvulsive therapy (ECT) is administered following general anaesthetic induction with methohexital, thiopental, etomidate, alfentanil, remifentanil, propofol or ketamine.
H.C. Özden, S.C. Gurel
doaj +1 more source
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition [PDF]
, 2014 Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a
Herd, Murray B. +5 more
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