Results 71 to 80 of about 15,180 (187)
European Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin +16 more
wiley +1 more source
The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro. [PDF]
PLoS ONE, 2018 (R)-2-methoxyethyl1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride (ET-26 HCl) is a novel etomidate analogue. The purpose of this study was to characterize whether ET-26 HCl could retain the superior myocardial performance of etomidate in vivo ...
Xingxing Liu +7 more
doaj +1 more source
Role of GABAA receptor subtypes in the behavioural effects of intravenous general anaesthetics [PDF]
, 2017 Since the introduction of general anaesthetics into clinical practice, researchers have been mystified as to how these chemically disparate drugs act to produce their dramatic effects on central nervous system function and behaviour. Scientific advances,
Lambert, J. J. +2 more
core +1 more source
Seminars in epileptology: Presurgical epilepsy evaluation
Epileptic Disorders, Volume 27, Issue 6, Page 1105-1147, December 2025.Abstract All patients with drug‐resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug ...
Stephan Schuele +11 more
wiley +1 more source
Effect of dexmedetomidine in preventing etomidate-induced myoclonus: a meta-analysis
Drug Design, Development and Therapy, 2017 Xueke Du,1 Chengmao Zhou,2 Linghui Pan,1 Changlong Li1 1Department of Anesthesiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, 2Department of Surgery, Zhaoqing Medical College, Zhaoqing Shi, Guangdong Sheng, People’s ...
Du X, Zhou C, Pan L, Li C
doaj
Chinese Medical Journal, 2016 Background: Etomidate (R-1-[1-ethylphenyl] imidazole-5-ethyl ester) is a widely used anesthetic drug that had been reported to contribute to cognitive deficits after general surgery. However, its underlying mechanisms have not been fully elucidated.
Xu Li +9 more
doaj +1 more source
Comparison of priming versus slow injection for reducing etomidate-induced myoclonus: a randomized controlled study [PDF]
Korean Journal of Anesthesiology, 2018 Background Etomidate injection is often associated with myoclonus. Etomidate injection technique influences the incidence of myoclonus. This study was designed to clarify which of the two injection techniques—slow injection or priming with etomidate—is ...
Parul Mullick +4 more
doaj +1 more source
Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study [PDF]
, 2012 At the start and during the course of electroconvulsive therapy (ECT), estimation of the seizure threshold (ST) is useful in weighing the expected effectiveness against the risks of side effects. Therefore, this study explores clinical factors predicting
Bastiaan Verwey +4 more
core +2 more sources
Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.Abstract Aim In Japan, drug‐related issues are diverse, and the use of cannabis and pharmaceuticals is rising. This study aimed to clarify the differences in clinical characteristics and treatment resource utilization by drug type. Methods We analyzed data from 891 individuals from the 2024 Nationwide Psychiatric Hospital Survey, which comprised 368 ...
Takashi Usami +4 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source