Results 91 to 100 of about 13,206 (170)

Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness [PDF]

, 2018
Breast cancer is highly aggressive and is the leading cause of cancer-related mortality in women in developed countries. The ETS proto-oncogene 1 (Ets1) has versatile roles during the cellular processes of cancer development. It is often highly expressed
Nan JH, Kim T, Verma R, IM, SIN HYEOG, DIPAYAN, RUDRA, Lee CG, Kwon, HK, Kim Y, Kim, GC, Kang K   +9 more
core   +1 more source

The transcription factors Ets1 and Sox10 interact during murine melanocyte development [PDF]

, 2015
Melanocytes, the pigment-producing cells, arise from multipotent neural crest (NC) cells during embryogenesis. Many genes required for melanocyte development were identified using mouse pigmentation mutants.
Hansen, Nancy F., Vemulapalli, Meghana, Lidia Kos, Dawn E. Watkins-Chow, NISC Compataive Sequencing Program, National Human Genome Research Institute, Pavan, William J., Amy Saldana-Caboverde, Meghana Vemulapalli, Watkins-Chow, Dawn E., NISC Comparative Sequencing Program,, James C. Mullikin, Perera, Erasmo M., Mullikin, James C., Nancy F. Hansen, William J. Pavan, Erasmo M. Perera, Kos, Lidia, NISC Comparative Sequencing Program, Saldana-Caboverde, Amy   +18 more
core   +1 more source

Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma.

PLoS Genetics, 2019
Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous disease of significant mortality and with limited treatment options. Recent genomic analysis of HNSCC tumors has identified several distinct molecular classes, of which the mesenchymal ...
Christian Gluck, Alexandra Glathar, Maria Tsompana, Norma Nowak, Lee Ann Garrett-Sinha, Michael J Buck, Satrajit Sinha   +6 more
doaj   +1 more source

Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker [PDF]

Man Ni,1,2 Weilong Peng,1,2 Xiaoguang Wang,1,2 Jingui Li1,2 1School of Veterinary Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, People’s ...
Peng W, Li J, Wang X, Ni M
core  

ETS1 Protein Expression May Be Altered by the Complementarity of ETS1 mRNA Sequences with miR-203a-3p and miR-204-3p in Papillary Thyroid Carcinoma

The expressions of ETS1, miR-203a-3p, and miR-204-3p in papillary thyroid carcinoma (PTC) are poorly described, and their clinical significance is unclear.
Sonja Šelemetjev, Tijana Išić Denčić, Stefana Stojanović Novković, Jelena Janković Miljuš, Vladan Živaljević, Marija Milinković, Duško Dunđerović   +6 more
core   +1 more source

Role of the transcription factor Ets1 in B lymphocyte differentiation

, 2022
Les lymphocytes B jouent un rôle central dans la réponse immunitaire en assurant la sécrétion d'anticorps. Elles sont générées à partir de cellules souches hématopoïétiques par un processus séquentiel hautement régulé qui assure la production des ...
Gama, Lydie
core  

Models of Ets1 binding to widely separated EBS.

, 2013
(A) Docking of Ets1 homodimer to nucleosomal DNA based on the superimposition of DNA in the (Ets1)2•2DNA structure and the high-resolution structure of a nucleosome core particle (PDB access code 1kx5) [49]. Ets1 molecules are displayed as blue and green
Nigar D. Babayeva (329636), Tahir H. Tahirov (329638), Oxana I. Baranovskaya (329637)   +2 more
core   +1 more source

ETS1 Promotes Context-Dependent Activation of Notch Signals in T-Cell Leukemia

, 2020
Notch is a signaling pathway involved in cellular growth and development. Aberrant activation of the Notch pathway is prevalent in cancer, including more than 60% of cases of T-cell acute lymphoblastic leukemia (T-ALL).
McCarter, Anna
core   +1 more source

Mechanism of lncRNA SNHG16 on kidney clear cell carcinoma cells by targeting miR-506-3p/ETS1/RAS/ERK molecular axis

Heliyon
Objective: This study aimed to investigate the mechanism of long noncoding ribonucleic acid (lncRNA) SNHG16 on kidney clear cell carcinoma (KIRC) cells by targeting miR-506-3p/ETS proto-oncogene 1, transcription factor (ETS1)/RAS/Extracellular regulated ...
Tao Cheng, Ming-Li Gu, Wei-Qiang Xu, Da-Wen Ye, Ze-Yu Zha, Wen-Ge Fang, Li-Kai Mao, Jing Ning, Xing-Bang Hu, Yong-Hui Ding   +9 more
doaj   +1 more source

The SAM domain of human TEL2 can abrogate transcriptional output from TEL1 (ETV-6) and ETS1/ETS2.

PLoS ONE, 2012
Regulation of gene expression downstream of the Receptor Tyrosine Kinase signaling pathway in Drosophila relies on a transcriptional effector network featuring two conserved Ets family proteins, Yan and Pointed, known as TEL1 (ETV6) and ETS1/ETS2 ...
Pavithra Vivekanand, Ilaria Rebay
doaj   +1 more source