Results 81 to 90 of about 13,453 (162)
BiomedicinesBackground/Objectives: Papillary thyroid carcinoma (PTC) is the most common malignancy of the endocrine system, characterized by various molecular alterations.
Stefana Stojanović Novković +6 more
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Molecular Oncology, 2020 Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and young adults. RMS exists as two major disease subtypes, oncofusion‐negative RMS (FN‐RMS) and oncofusion‐positive RMS (FP‐RMS). FP‐RMS is characterized by recurrent PAX3/7‐FOXO1
Lays M. Sobral +8 more
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ETS1 and SP1 are the direct targets of miR-324-5p.
, 2015 A. Schematic representation of the mature miR-324-5p sequence, miR-324-5p target site in the 3'-UTR of ETS1 and SP1 mRNA and a 3'-UTR mutant of ETS1 and SP1 mRNA containing three altered nucleotides in the putative target site (shown as ETS1 or SP1-3'UTR-
Binhui Xie (770873) +8 more
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Ets1 is expressed in β-cells, but not in α-cells in mouse pancreas.
, 2014 (A). Paraffin-embedded pancreas sections from 16 weeks old mice fed chow diet were subjected to immunofluorescence analysis with rabbit anti-Ets1 antibody together with either mouse anti-insulin (top) or anti-glucagon (bottom) antibodies.
Yan-Shan Dai (572516) +9 more
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ETS1 is highly expressed in HNSCC tumors and is associated with poor patient survival.
, 2019 Boxplots displaying the distribution of ETS1 probe intensity, across Normal, Dysplastic and Cancerous Tissue, in the (A) Peng et al. (2011), (p = 5.16e-10) and the (B) Chen et al. (2008) microarray datasets, (p = 3.6e-6, p = 2.46e-4).
Maria Tsompana (3037167) +6 more
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Models of Ets1 binding to widely separated EBS.
, 2013 (A) Docking of Ets1 homodimer to nucleosomal DNA based on the superimposition of DNA in the (Ets1)2•2DNA structure and the high-resolution structure of a nucleosome core particle (PDB access code 1kx5) [49]. Ets1 molecules are displayed as blue and green
Nigar D. Babayeva (329636) +2 more
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Mae suppresses transcriptional activation by ETS1/2 in Drosophila S2 cells.
, 2013 (A) Activation of the argos-luciferase reporter by ETS1/2 is enhanced by expression of RasV12 and inhibited by Mae. (B) Myc-Mae coimmunoprecipitated with Flag-ETS1/2 from lysates of cotransfected Drosophila S2 cells cotransfected (lanes 2 and 3) but not ...
Ilaria Rebay (23707) +1 more
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PLoS Genetics, 2019 Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous disease of significant mortality and with limited treatment options. Recent genomic analysis of HNSCC tumors has identified several distinct molecular classes, of which the mesenchymal ...
Christian Gluck +6 more
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, 2019 Epithelial-mesenchymal transition (EMT) is an embryonic program that is reactivated in cancer and regulates the invasion and metastasis of tumor cells. Zinc finger E-box binding homeobox 2 (ZEB2) induces EMT by upregulating matrix metalloproteinases (MMP)
Odabas, Gorkem +13 more
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M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1
Nature CommunicationsAdipose tissue macrophages can promote beige adipose thermogenesis by altering local sympathetic activity. Here, we perform sympathectomy in mice and further eradicate subcutaneous adipose macrophages and discover that these macrophages have a direct ...
Suyang Wu +13 more
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