Results 71 to 80 of about 13,453 (162)
Advanced Science, Volume 13, Issue 57, 14 October 2026.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Ets1, a Key Regulator of TFH2 Cell Differentiation
, 2019 E26 transformation-specific-1 (Ets1) is a member of the Ets family of transcription factors and plays important functions in the development, proliferation, and survival of immune cells.
IM, SIN HYEOG
core
This data presents additional confocal single channel and merged images for Supplementary Figure S8A -SK-N-MC-CRISPRa-ETS1-Vinculin and TNS3.
Natasha J. Caplen (14913966) +2 more
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ApoE lipidation state directs immunometabolic reprogramming of human microglia
Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.Abstract INTRODUCTION ApoE ε4 is the strongest genetic risk factor for Alzheimer's disease (AD). Emerging evidence suggests that ApoE4 increases AD risk by disrupting microglial metabolism and function. However, whether ApoE lipidation state contributes to microglial dysfunction remains poorly understood. METHODS Human microglia were treated with lipid‐
Tsion G. Shiferaw +14 more
wiley +1 more source
Ets1, a Guardian of T Follicular Helper Cell Differentiation and SLE Development
, 2019 E26 transformation-specific-1 (Ets1) is a member of the Ets family of transcription factors and plays important functions in the development, proliferation, and survival of immune cells.
IM, SIN HYEOG
core
, 2019 Figure S4. Mechanisms of HuR-involved regulation of ETS1. a YTHDF2 was knockdown in PLC/PRF/5 without any variation in ETS1 expression; b and c WTAP was knockdown followed by qRT-PCR (b) and western blotting (c) to estimate the alteration of HuR; d WTAP ...
Longfei Dai (7302221) +13 more
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Loss, persistence and reversal of phenotypic traits
Biological Reviews, Volume 101, Issue 5, Page 2119-2133, October 2026.ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
wiley +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.ABSTRACT Background Sepsis reshapes inflammatory, immune, and metabolic activity, yet the behavior of genes linked to growth hormone biology within this response has not been well defined. We therefore searched for growth hormone‐related genes (GHRGs) that could distinguish sepsis and asked whether the resulting markers also reflected variation in host
Xiuhua Li +4 more
wiley +1 more source
Structural studies on Ets1 and USF1 transcription factor complexes with DNA [PDF]
, 2005 Ets1 und USF1 sind Transkriptionsfaktoren, die in der Regulierung der Transkription unter der Kontrolle von viralen und zellulären Promotoren eine wichtige Rolle spielen.
Lamber, Ekaterina
core +1 more source
ETS1 Haplotype analysis on SLE association.
, 2013 ETS1 Haplotype analysis on SLE association.
Nattiya Hirankarn (215382) +30 more
core +1 more source