Results 61 to 70 of about 13,453 (162)
This data presents additional confocal single channel and merged images for Supplementary Figure S8B ES-5838-CRISPRa-ETS1-Vinculin and TNS3.
Natasha J. Caplen (14913966) +2 more
core +1 more source
Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers
Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley +1 more source
Varicose veins are the most common venous disorder in humans and are characterized by hemodynamic instability due to valvular insufficiency and orthostatic lifestyle factors. It is unclear how changes in biomechanical signals cause aberrant remodeling of
B.J. Sreelakshmi +5 more
doaj +1 more source
Ets family proteins regulate the EMT transcription factors Snail and ZEB in cancer cells
The epithelial–mesenchymal transition (EMT) is a crucial morphological event that occurs during epithelial tumor progression. Snail and ZEB1/2 (ZEB1 and ZEB2), known as EMT transcription factors, are key regulators of this transition.
Mai Koizumi Ichikawa +8 more
doaj +1 more source
This data presents additional confocal single channel and merged images for Supplementary Figure S9B ES-5838-CRISPRa-ETS1-Actin and TNS3.
Natasha J. Caplen (14913966) +2 more
core +1 more source
Mutations in and reduced expression of the ETS1 gene may be associated with systemic lupus erythematosus (SLE). Here, we report a replication study to investigate associations of eight ETS1 single-nucleotide polymorphisms in the 3′-untranslated region (3′
Bangpin Pan (6855194) +3 more
core +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
This data presents additional confocal single channel and merged images for Supplementary Figure S9A SK-N-MC-CRISPRa-ETS1-Actin and TNS3.
Natasha J. Caplen (14913966) +2 more
core +1 more source
Objective To explore the roles of transcription factor E26 transformation-specific 1 (ETS1) and F-box protein 45 (FBXO45) in invasion and metastasis in hepatocellular carcinoma cells and the potential molecular mechanism.
ZHU Zhenbao, WU Feifan, GU Yongpeng
doaj +1 more source
Ets2 Is an Activity‐Dependent Transcriptional Regulator of a Fast‐Twitch Muscle Program [PDF]
Ets2 is a transcription factor rapidly (24 h) upregulated in skeletal muscle by fast 150 Hz, but not slow 20 Hz, stimulation patterns. Ets2 selectively translocates to nuclei of slow soleus muscle when stimulated by fast‐patterned, but not slow‐patterned, activity. Ets2 binds to a consensus DNA sequence in the troponin I fast intronic enhancer (TnIFIRE)
Rana Z +9 more
europepmc +2 more sources

