Results 61 to 70 of about 13,206 (170)

LncRNA LINC00963 promotes osteogenic differentiation of hBMSCs and alleviates osteoporosis progression by targeting miRNA-760/ETS1 axis

open access: yesAutoimmunity, 2021
Although long non-coding RNA LINC00963 has been reported to play a crucial regulatory role in osteoporosis (OP), its specific mechanism has not been well studied.
Lirong Ren   +5 more
doaj   +1 more source

Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
Cancer stem cell quiescence is a regulated, reversible survival mechanism, preserving stemness and promoting therapy resistance through intrinsic programs and niche signals. Targeting these pathways holds promise for eradicating quiescent CSCs and preventing recurrence.
Yasin Ahmadi   +3 more
wiley   +1 more source

Ebegboni...Caplen Additional replicates for Supplementary Figure S8B ES-5838-CRISPRa-ETS1-Vinculin and TNS3

open access: yes
This data presents additional confocal single channel and merged images for Supplementary Figure S8B ES-5838-CRISPRa-ETS1-Vinculin and TNS3.
Natasha J. Caplen (14913966)   +2 more
core   +1 more source

Ebegboni...Caplen Additional replicates for Supplementary Figure S9B ES-5838-CRISPRa-ETS1-Actin and TNS3

open access: yes
This data presents additional confocal single channel and merged images for Supplementary Figure S9B ES-5838-CRISPRa-ETS1-Actin and TNS3.
Natasha J. Caplen (14913966)   +2 more
core   +1 more source

Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling

open access: yesEuropean Journal of Cell Biology
Varicose veins are the most common venous disorder in humans and are characterized by hemodynamic instability due to valvular insufficiency and orthostatic lifestyle factors. It is unclear how changes in biomechanical signals cause aberrant remodeling of
B.J. Sreelakshmi   +5 more
doaj   +1 more source

Exploratory single‐nucleus multiomics analysis of myeloid cell states associated with neoadjuvant chemotherapy response in pancreatic ductal adenocarcinoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Neoadjuvant‐treated PDAC tumors were stratified into responders and non‐responders based on CAP guidelines snRNA‐seq, snATAC‐seq, and spatial transcriptomics can be used to profile the neoadjuvant‐chemotherapy‐treated PDAC immune landscape. Our exploratory findings nominate candidate myeloid features for validation in larger cohorts and functional ...
Mercy Ojetunde   +11 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

Ebegboni...Caplen Additional replicates for Supplementary Figure S9A SK-N-MC-CRISPRa-ETS1-Actin and TNS3

open access: yes
This data presents additional confocal single channel and merged images for Supplementary Figure S9A SK-N-MC-CRISPRa-ETS1-Actin and TNS3.
Natasha J. Caplen (14913966)   +2 more
core   +1 more source

ETS1 knockdown counteracts high-glucose induced reduction of VPC numbers.

open access: yes, 2013
Mononuclear cells were transfected with ETS1-specific siRNA (ets1), a scrambled control (scr) at day 0 or left untransfected and stimulated with glucose. After 3 days of culture, VPC were stained and counted by independent investigators (left side). Data
Judith Haendeler (264054)   +5 more
core   +1 more source

ETS1 transcription up-regulates FBXO45 and promotes invasion and migration of hepatocellular carcinoma via epithelial-mesenchymal transition

open access: yes陆军军医大学学报
Objective‍ ‍To explore the roles of transcription factor E26 transformation-specific 1 (ETS1) and F-box protein 45 (FBXO45) in invasion and metastasis in hepatocellular carcinoma cells and the potential molecular mechanism.
ZHU Zhenbao, WU Feifan, GU Yongpeng
doaj   +1 more source

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