Results 61 to 70 of about 3,703 (283)

Development of a thermal-hydraulic model of the EU-DEMO Water Cooled Lithium Lead Breeding Blanket Primary Heat Transport System [PDF]

, 2023
The EUROfusion consortium is developing the project of a DEMOnstration Fusion Reactor (EU-DEMO) which would follow ITER in the pathway towards the quest for the exploitation of fusion energy.
Quartararo A., Moscato I., Vacca S., Di Maio P. A., Bongiovì G., Vallone E.   +5 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Patenting in Europe: The Jurisdiction of the CJEU over European Patent Law

Perspectives on Federalism, 2015
This paper will deal with EU competence over patent law, especially in the context of the TRIPS Agreement with reference to the ruling of CJEU in the Daiichi Sankyo case (CJEU case C-414/11 Daiichi Sankyo v DEMO Anonimos). The first part will explain the
Minn Mari
doaj   +1 more source

STEAM Experimental Facility: A Step Forward for the Development of the EU DEMO BoP Water Coolant Technology

Energies, 2023
Within the EUROfusion roadmap for the technological development of the European-DEMOnstration (EU-DEMO) reactor, a key point has been identified in the discontinuous operation (pulse-dwell-pulse) of the machine.
Alessandra Vannoni, Pierdomenico Lorusso, Pietro Arena, Marica Eboli, Ranieri Marinari, Amelia Tincani, Cristiano Ciurluini, Fabio Giannetti, Nicolò Badodi, Claudio Tripodo, Antonio Cammi, Luciana Barucca, Andrea Tarallo, Pietro Agostini, Alessandro Del Nevo   +14 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Definition of an EU-DEMO design point robust to epistemic plasma physics uncertainties

Nuclear Fusion
A novel approach for explicitly and robustly accounting for epistemic uncertainties in plasma confinement in the 0D design of tokamaks is presented, in which the plasma safety factor at the 95th percentile flux surface, q _95 , is used to apply a design ...
M. Coleman, H. Zohm, C. Bourdelle, F. Maviglia, A.J. Pearce, M. Siccinio, A. Spagnuolo, S. Wiesen   +7 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

A Sensitivity Analysis on Design of the EU-DEMO Steady-State Electrical Power Distribution Grid via Monte Carlo-Based Probabilistic Power Flow Models

IEEE Access
The EU-DEMO (EUropean DEMOnstration Power Plant) fusion reactor is one of the most ambitious energy projects aiming at demonstrating the feasibility of nuclear fusion to be a clean, safe, and sustainable source of energy.
M. Caldora, S. Panella, M. C. Falvo, S. Minucci, A. Ferro, T. Franke   +5 more
doaj   +1 more source

Thermo-Mechanical Analysis and Design Update of the Top Cap Region of the DEMO Water-Cooled Lithium Lead Central Outboard Blanket Segment

Applied Sciences, 2022
Within the framework of the EUROfusion research and development activities, the Water-Cooled Lithium Lead (WCLL) Breeding Blanket (BB) is one of the two candidates to be chosen as the driver blanket for the European DEMO nuclear fusion reactor. Hence, an
Gaetano Bongiovì, Salvatore Giambrone, Ilenia Catanzaro, Pietro Alessandro Di Maio, Pietro Arena   +4 more
doaj   +1 more source